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Assessment of the relationship between reperfusion success and T-peak to T-end interval in patients with ST elevation myocardial infarction treated with percutaneous coronary intervention [Anatol J Cardiol]
Anatol J Cardiol. 2018; 19(1): 50-57 | DOI: 10.14744/AnatolJCardiol.2017.7949  

Assessment of the relationship between reperfusion success and T-peak to T-end interval in patients with ST elevation myocardial infarction treated with percutaneous coronary intervention

Metin Çağdaş1, Süleyman Karakoyun1, Ibrahim Rencüzoğulları1, Yavuz Karabağ1, Mahmut Yesin2, Yalçın Velibey3, Inanç Artaç1, Doğan Iliş1, Süleyman Çağan Efe4, Onur Taşar5, Halil Ibrahim Tanboğa6
1Department of Cardiology, Faculty of Medicine, Kafkas University; Kars-Turkey
2Department of Cardiology, Kars Harakani State Hospital; Kars-Turkey
3Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital; İstanbul-Turkey
4Department of Cardiology, Ağrı State Hospital; Ağrı-Turkey
5Department of Cardiology, Elazığ Education and Research Hospital; Elazığ-Turkey
6Department of Cardiology, Faculty of Medicine, Atatürk University; Erzurum-Turkey

Objective: T-peak–T-end (TPE) interval, which represents the dispersion of repolarization, is defined as the interval between the peak and end of the T-wave, and is associated with increased malignant ventricular arrhythmia and sudden cardiac death (SCD) in patients with ST elevation myocardial infarction (STEMI). Although prolonged TPE interval is associated with poor short- and long-term outcomes, even in patients with STEMI treated with successful primary percutaneous coronary intervention (pPCI), clinical, angiographic, and laboratory parameters that affect TPE remain to be elucidated. The aim of our study was to evaluate the potential relationship between prolonged TPE interval and reperfusion success using ST segment resolution (STR) in patients with STEMI undergoing pPCI.
Methods: In the current study, 218 consecutive patients with STEMI who underwent pPCI were enrolled; after exclusion, 164 patients were included in the study population.
Results: Patients were divided into two groups according to the presence of complete (STR%≥70) or incomplete (STR%<70) STR. Preprocedural corrected TPE (cTPEPRE;116±21 ms vs. 108±21 ms; p=0.027), postprocedural TPE (TPEPOST; 107±16 ms vs. 92±21 ms; p<0.001), and postprocedural cTPE (cTPEPOST; 119±19 ms vs. 102±17 ms; p<0.001) intervals were significantly longer in patients with incomplete STR than in patients with complete STR, whereas there was no statistically significant difference between the two groups in terms of pre- and postprocedural and corrected QT intervals. cTPEPRE and cTPEPOST were found to be independent predictors for incomplete STR.
Conclusion: To our knowledge, this is the first study that evaluated the relationship between TPE interval and no-reflow defined by STR in patients with STEMI who were treated with pPCI.

Keywords: ST elevation myocardial infarction, reperfusion, no-reflow, T-peak–T-end interval


Metin Çağdaş, Süleyman Karakoyun, Ibrahim Rencüzoğulları, Yavuz Karabağ, Mahmut Yesin, Yalçın Velibey, Inanç Artaç, Doğan Iliş, Süleyman Çağan Efe, Onur Taşar, Halil Ibrahim Tanboğa. Assessment of the relationship between reperfusion success and T-peak to T-end interval in patients with ST elevation myocardial infarction treated with percutaneous coronary intervention. Anatol J Cardiol. 2018; 19(1): 50-57

Corresponding Author: Metin Çağdaş


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