ISSN 2149-2263 | E-ISSN 2149-2271
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Isolation ratio and T- serotyping of group A streptococci from pediatric upper respiratory tract infections in Turkey [Anatol J Cardiol]
Anatol J Cardiol. 2005; 5(4): 302-304

Isolation ratio and T- serotyping of group A streptococci from pediatric upper respiratory tract infections in Turkey

Aynur Eren Topkaya1, Sinan Arsan2
1Department of Microbiology and Clinical Microbiology, Faculty of Medicine, University of Maltepe, Istanbul Turkey
2Marmara Üniversitesi Tıp Fakültesi Kalp ve Damar Cerrahisi Anabilim Dalı, İstanbul Türkiye

Objective: Acute rheumatic fever can follow throat infections with group A streptococci. Certain serotypes of group A streptococci such as M1, M3, M5, M6, M14, M18, M19, M24 are associated with this disorder. Immunity to streptococci and to rheumatic fever depends on antibodies to the M proteins. Due to current scarcity of M-typing sera, many laboratories use T typing and opacity factor production for serotype identification of group A streptococci. In order to, investigate the most common serotypes of group A streptococci in our country in recent years we studied T-agglutination typing and opacity factor of 120 group A streptococci strains isolated from throat cultures of 930 children. Methods: Diffuse, stable suspensions of group A streptococci were tested with polyvalent antisera (T,U,W,X,Y) by slide agglutination. Microplate method was used for opacity factor detection. Results: T-protein -agglutination patterns U ( 2,4,6,28 ) were the most common among typeable strains. The rate of T-protein -agglutination patterns T ( 1,3,13, B3264 ) and X ( 8,14,25,Imp.19 ) were 20 % and 18 % respectively. Opacity factor production rate of isolated group A streptococci strains was 65 %. Conclusion: To profit global assessment of rheumatic fever and rheumatic heart disease, more epidemiologic and serotyping research is required in our country.

Keywords: Group A streptococcus, isolation rate, serotyping

Aynur Eren Topkaya, Sinan Arsan. Isolation ratio and T- serotyping of group A streptococci from pediatric upper respiratory tract infections in Turkey. Anatol J Cardiol. 2005; 5(4): 302-304
Manuscript Language: English


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