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Tips for management of arrhythmias in endocrine disorders from European Heart Rhythm Association position paper [Anatol J Cardiol]
Anatol J Cardiol. Ahead of Print: AJC-87260 | DOI: 10.14744/AnatolJCardiol.2018.87260  

Tips for management of arrhythmias in endocrine disorders from European Heart Rhythm Association position paper

Emin Evren Özcan1, Muhammet Dural2, Bülent Görenek2
1Dokuz Eylül University, Department of Cardiology, İzmir, Turkey
2Eskisehir Osmangazi University, Department of Cardiology, Eskişehir, Turkey

In endocrine diseases; hormonal changes, electrolyte abnormalities and deterioration of heart structure can lead to various arrhythmias. In diabetic patients; hypoglycemia, hyperglycemia, and hypokalemia can trigger arrhythmias, and diabetic cardiomyopathy can also cause electrical and structural remodeling and form a substrate for arrhythmias. The risk of atrial fibrillation (AF) increases in hyperthyroidism while the prevalence of ventricular arrhythmias in hypothyroidism is higher. Besides AF and ventricular tachycardias, bradycardias and atrioventricular blocks can also be seen in pheochromocytoma due to desensitization of adrenergic cardiovascular receptors. Correction of metabolic and electrolyte disturbances in those with adrenal cortex disease should be the main approach in the prevention and treatment of arrhythmias. Early initiation of treatment in patients with acromegaly seems to decrease the development of cardiac remodeling and ventricular arrhythmia. Early and late afterdepolarizations due to hypercalcemia in hyperparathyroidism can lead to life-threatening ventricular arrhythmias. This elegant position paper provides important recommendations regarding prevention and treatment of arrhythmias for each specific endocrine disorder.

Keywords: European Heart Rhythm Association, arrhythmias, endocrine disorders


Avrupa Kalp Ritim Birliği uzlaşı raporundan endokrin hastalıklarında aritmilerin yönetimi için ipuçları

Emin Evren Özcan1, Muhammet Dural2, Bülent Görenek2
1Dokuz Eylül University, Department of Cardiology, İzmir, Turkey
2Eskisehir Osmangazi University, Department of Cardiology, Eskişehir, Turkey

In endocrine diseases; hormonal changes, electrolyte abnormalities and deterioration of heart structure can lead to various arrhythmias. In diabetic patients; hypoglycemia, hyperglycemia, and hypokalemia can trigger arrhythmias, and diabetic cardiomyopathy can also cause electrical and structural remodeling and form a substrate for arrhythmias. The risk of atrial fibrillation (AF) increases in hyperthyroidism while the prevalence of ventricular arrhythmias in hypothyroidism is higher. Besides AF and ventricular tachycardias, bradycardias and atrioventricular blocks can also be seen in pheochromocytoma due to desensitization of adrenergic cardiovascular receptors. Correction of metabolic and electrolyte disturbances in those with adrenal cortex disease should be the main approach in the prevention and treatment of arrhythmias. Early initiation of treatment in patients with acromegaly seems to decrease the development of cardiac remodeling and ventricular arrhythmia. Early and late afterdepolarizations due to hypercalcemia in hyperparathyroidism can lead to life-threatening ventricular arrhythmias. This elegant position paper provides important recommendations regarding prevention and treatment of arrhythmias for each specific endocrine disorder.

Anahtar Kelimeler: European Heart Rhythm Association, arrhythmias, endocrine disorders




Corresponding Author: Bülent Görenek, Türkiye


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