Comparison of application of 2013 ACC/AHA guideline and 2011 European Society of Cardiology guideline for the management of dyslipidemias for primary prevention in a Turkish cohortMustafa Yılmaz1, İlyas Atar1, Senem Hasırcı2, Kadirhan Akyol1, Abdullah Tekin1, Emir Karaçağlar1, Orçun Çiftçi1, Haldun Müderrisoğlu1
1Department of Cardiology, Faculty of Medicine, Başkent University; Adana-Turkey
2Department of Cardiology, Nizip State Hospital; Gaziantep-Turkey
Objective: Atherosclerotic cardiovascular disease is a major global cause of death. The common approach in primary prevention of cardiovas- cular disease is to identify patients at high risk for cardiovascular disease. This article analyzes and compares the application of 2013 American College of Cardiology/American Heart Association (ACC/AHA) guideline and the 2011 European Society of Cardiology (ESC) guideline for the management of dyslipidemias for primary prevention in Turkish population.Keywords: guidelines, preventive cardiology, statins, dyslipidemias
Methods: The study included 833 patients (482 women and 351 men). Risk scores were calculated according to both guidelines and indications for statin treatment were determined according to sex and age group. Variables are presented as mean±SD or median with interquartile range for continuous data and as proportions for categorical data. Variables were analyzed by unpaired t-test, Mann-Whitney U test, chi-square or Fischers exact test as appropriate.
Results: The ACC/AHA would suggest statin treatment in 415 patients out of 833 (49.5%), while ESC would recommend statin for 193 patients out of 833 (23.1%) (p<0.001). Statins would be recommended for 40.4% of women and 62.6% of men for primary prevention by the ACC/AHA, while this figure was 12% for women and 38.4% for men according to the ESC guideline (p<0.001 for both).
Conclusion: When compared to the ESC guideline, the ACC/AHA guideline suggests augmented statin treatment for primary prevention in Turk- ish population. (Anatol J Cardiol 2017; 17: 92-6)
Mustafa Yılmaz, İlyas Atar, Senem Hasırcı, Kadirhan Akyol, Abdullah Tekin, Emir Karaçağlar, Orçun Çiftçi, Haldun Müderrisoğlu. Comparison of application of 2013 ACC/AHA guideline and 2011 European Society of Cardiology guideline for the management of dyslipidemias for primary prevention in a Turkish cohort. Anatol J Cardiol. 2017; 17(2): 92-96
Corresponding Author: Mustafa Yılmaz, Türkiye