The Anatolian Journal of Cardiology
Review

A global perspective on mechanical prosthetic heart valve thrombosis: Diagnostic and therapeutic challenges

Anatol J Cardiol 2016; 16: 980-989
DOI: 10.14744/AnatolJCardiol.2016.7486
Read: 255 Downloads: 147 Published: 01 July 2021

Prosthetic valve thrombosis is one of the major causes of primary valve failure, which can be life-threatening. Multimodality imaging is neces- sary for determination of leaflet immobilization, cause of underlying pathology (thrombus versus pannus or both), and whether thrombolytic therapy attempt in the patient would be successful or surgery is needed. Current guidelines for the management of prosthetic valve thrombosis lack definitive class I recommendations due to lack of randomized controlled trials, and usually leave the choice of treatment to the clinician’s experience. In this review, we aimed to summarize the pathogenesis, diagnosis, and management of mechanical prosthetic valve thrombosis. (Anatol J Cardiol 2016; 16: 980-9)

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