ISSN 2149-2263 | E-ISSN 2149-2271
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Serum lipid profiles including non-high density lipoprotein cholesterol levels in Turkish school-children [Anatol J Cardiol]
Anatol J Cardiol. 2007; 7(4): 415-420

Serum lipid profiles including non-high density lipoprotein cholesterol levels in Turkish school-children

Birsen Uçar1, Zübeyir Kılıç1, Ener Çağrı Dinleyici2, Ömer Çolak3, Erdoğan Güneş2
1Department of Pediatric Cardiology, Eskişehir Osmangazi University, Faculty of Medicine, Eskişehir, Turkey
2Pediatrics, Eskişehir Osmangazi University, Faculty of Medicine, Eskişehir, Turkey
3Biochemistry, Eskişehir Osmangazi University, Faculty of Medicine, Eskişehir, Turkey

Objective: Early detection of dyslipidemia and long-term prevention of atherosclerosis by controlling risk factors should begin in childhood. The purpose of this study was to evaluate the prevalence of dyslipidemia according to non-high density lipoprotein cholesterol (non-HDL-C) levels in children and also evaluate serum non-HDL-C levels according to age groups, gender difference and living areas. Methods: Overall, 2896 children (1467 girls, 1429 boys) aged between 7-18 years, residing in urban and rural parts of Eskişehir, Turkey, were enrolled in this randomized cross-sectional study. Serum non-HDL-C, total cholesterol (TC) and triglyceride (TG) levels were assessed in all participants of the study. Statistical analysis was performed Student's independent-samples T test for comparison of lipid parameters and relations between lipid parameters and age, anthropometric measurements, body fat percentage were evaluated by Pearson correlation test. Results: Serum non-HDL-C levels were significantly higher in girls (115.5±31.5mg/dl) than boys (106.7±30.2 mg/Dl) (p<0.001). For girls, serum non-HDL-C levels were higher in 7-10 year age group than in 11-14-year and 15-18-year age groups (p<0.01 and p<0.05, respectively). For boys serum non-HDL-C levels of 7-10 year age group were significantly higher than in 11-14-year and 15-18-year age groups (p<0.001 for both). Serum non-HDL-C, total cholesterol and triglyceride levels were higher in girls than in boys especially in the 7-10-year-old age group. Serum TC, LDL-C, and HDL-C levels were higher in urban area residents, while serum TG levels were higher in rural area residents (p<0.001). Serum non-HDL-C levels were similar in residents of different living areas (p>0.05). In both sexes, non-HDL-C levels positively correlated with age and lipid parameters except HDL-C levels and also negatively correlated with HDL-C levels. In boys, non-HDL-C levels also correlated with total body fat percentage, weight, height. The prevalence of dyslipidemia according to non-HDL-C levels was higher (13.2%) in girls than boys (8.9%) (p<0.001). The prevalence of elevated non-HDL-C levels was higher in urban area residents than in rural area residents (p<0.05). The dyslipidemia prevalence according to non-HDL-C levels was similar with dyslipidemia prevalence according to serum LDL-C levels. Conclusion: Our results are indicative of the prevalence of dyslipidemia in children is considerably common in our population. Serum non-HDL-C levels could be used as an appropriate tool for detecting dyslipidemia in childhood.

Keywords: Children, lipid, lipoprotein, non-HDL, Turkey

Birsen Uçar, Zübeyir Kılıç, Ener Çağrı Dinleyici, Ömer Çolak, Erdoğan Güneş. Serum lipid profiles including non-high density lipoprotein cholesterol levels in Turkish school-children. Anatol J Cardiol. 2007; 7(4): 415-420

Corresponding Author: Ener Çağrı Dinleyici, Türkiye
Manuscript Language: English


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Journal Citation Indicator: 0.18
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