ISSN 2149-2263 | E-ISSN 2149-2271
pdf
Impact of the Total Ischemia Time on No-Reflow Phenomenon in Patients with ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention [Anatol J Cardiol]
Anatol J Cardiol. 2022; 26(5): 382-387 | DOI: 10.5152/AnatolJCardiol.2021.846

Impact of the Total Ischemia Time on No-Reflow Phenomenon in Patients with ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Mohamed Khalfallah, Amany Allaithy, Dina Abdelsalam
Department of Cardiovascular Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt

Background: No-reflow phenomenon after primary percutaneous coronary intervention is a common condition affecting the outcomes; therefore, studying its predictive factors is helpful in identifying patients at high risk. Our objective was to investigate the impact of the total ischemia time on no-reflow phenomenon and its correlation to thrombolysis in myocardial infarction flow grade after primary percutaneous coronary intervention.

Methods: This study was conducted on 545 patients with ST-elevation myocardial infarction who underwent PPCI; the patients were divided into two groups according to the incidence of no-reflow, TIMI flow ≤2 was considered no-reflow. The time interval from chest pain onset to balloon dilatation was assessed and correlated to thrombolysis in myocardial infarction flow grade.

Results: The incidence of no-reflow was 13.9%; thrombolysis in myocardial infarction flow ≤2 occurred in 76 patients. Multivariate regression analysis showed that advanced age 65 years, the total ischemia time ˃6 h, high thrombus burden, and cardiogenic shock were the independent predictors of no-reflow phenomenon. Spearman’s correlation analysis showed a significant negative correlation between the total ischemia time and thrombolysis in myocardial infarction flow grade (r = −351 and P-value =.001).

Conclusion: The time delay is the main limitation of achieving thrombolysis in myocardial infarction 3 flow after primary percutaneous coronary intervention. The total ischemia time has a significant negative correlation with thrombolysis in myocardial infarction flow grade after primary percutaneous coronary intervention.

Keywords: Impact, the total ischemia time, no-reflow phenomenon, ST-elevation myo-cardial infarction, primary percutaneous coronary intervention

Mohamed Khalfallah, Amany Allaithy, Dina Abdelsalam. Impact of the Total Ischemia Time on No-Reflow Phenomenon in Patients with ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. Anatol J Cardiol. 2022; 26(5): 382-387

Corresponding Author: Mohamed Khalfallah, Egypt
Manuscript Language: English


Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
per Paper:
0.22
SCImago Journal Rank: 0.348

Quick Search



Copyright © 2024 The Anatolian Journal of Cardiology



Kare Publishing is a subsidiary of Kare Media.