EDITORIAL | |
1. | This month in the journal: cardiology and other disciplines Zeki Öngen PMID: 27282670 PMCID: PMC5331366 doi: 10.14744/AnatolJCardiol.2016.06 Page 369 Abstract |Full Text PDF |
HOT TOPIC | |
2. | Determinants of prevalence, awareness, treatment and control of high LDL-C in Turkey Kaan Sözmen, Belgin Ünal, Sibel Sakarya, Gönül Dinç, Nazan Yardım, Banu Ekinci, Gül Ergör PMID: 27282671 PMCID: PMC5331367 doi: 10.14744/AnatolJCardiol.2016.7018 Pages 370 - 384 Objective: High blood cholesterol is one of the main modifiable risk factors for cardiovascular diseases (CVDs). The aim of the study is to determine the factors associated with the prevalence, awareness, treatment, and control of high “low-density lipoprotein-cholesterol” (LDL-C) among adults aged ≥20 years in Turkey. Methods: We used data from Chronic Diseases and Risk Factors Survey conducted in 2011–2012. The presence of high LDL-C, lipid-lowering treatment eligibility, and achievement of target LDL-C were defined according to the third Adult Treatment Panel guidelines on treatment of high cholesterol. Multivariate logistic regression analyses were performed to determine the associations between participant characteristics and high LDL-C prevalence, awareness, treatment, and control. Results: Framingham risk score categorization was performed for 13121 individuals aged ≥20 years. Approximately, 28% of the participants presented with high LDL-C. Among those with high LDL-C, 55.8% were aware of their situation; among those aware of high LDL-C, 46.9% were receiving lipidlowering medication, and 50.6% of individuals who were receiving treatment achieved target LDL-C levels on the basis of their coronary heart disease (CHD) risk. Control of high LDL-C was negatively associated with the presence of diabetes mellitus (odds ratio: 0.36, 95% CI: 0.27–0.49, p<0.001). Conclusion: Despite the high awareness rates, there was a high proportion of adults who did not receive treatment or achieve recommended levels of LDL-C during treatment. The low treatment and control levels among individuals based on their CHD risk levels call for a better application of recommendations regarding personal preventive measures and treatments in Turkey. (Anatol J Cardiol 2016; 16: 000-00) |
ORIGINAL INVESTIGATION | |
3. | Everolimus (RAD001) inhibits the proliferation of rat vascular smooth muscle cells by up-regulating the activity of the p27/kip1 gene promoter Boli Ran, Minfeng Li, Yeqing Li, Yang Lin, Weimin Liu, Qiulin Luo, Yongxin Fu, Qianmei Tang, Ya Yang, Yunfei Pu PMID: 27163533 PMCID: PMC5331368 doi: 10.14744/AnatolJCardiol.2015.6426 Pages 385 - 391 Objective: We investigated whether the inhibitory effect of the immunosuppressant everolimus (RAD001) on vascular smooth muscle cell (VSMC) proliferation is mediated by p27/kip1 gene promoter activity. Methods: In this experimental study, cultured rat VSMCs were transiently transfected with a recombinant plasmid (pXp27) containing p27/kip1 gene promoter sequence and a chloramphenicol acetyltransferase (CAT) reporter gene. After stimulation with the mitogen platelet-derived growth factor (PDGF-BB, 10 ng/mL) in the presence or absence of RAD001 (10 nM), the promoter activity, mRNA expression, and protein expression of p27/kip1 were examined by CAT assay, RT–PCR, and immunoblotting, respectively. Cell cycle–related changes were detected by flow cytometry. DNA synthesis was determined using 3H-TdR incorporation. Results: Compared with the non-stimulation group, PDGF-BB stimulation induced a significant proliferative response in the VSMCs as indicated by decreased p27/kip1 gene promoter activity, decreased p27/kip1 mRNA and protein expression, increased S-phase and G2/M-phase cells, and increased DNA synthesis. RAD001 intervention increased p27/kip1 gene promoter activity 3.5-fold, promoted p27/kip1 mRNA and protein expression, increased G0-phase cells, reduced DNA synthesis, and, overall, inhibited PDGF-BB–stimulated cell proliferation. Conclusion: RAD001 inhibits PDGF-BB–stimulated proliferation of cultured VSMCs by upregulating p27/kip1 gene promoter activity and increasing p27/kip1 mRNA and protein expression. (Anatol J Cardiol 2016; 16: 385-91) |
4. | Circulating microRNAs in patients with ST-elevation myocardial infarction Ufuk Eryılmaz, Çağdaş Akgüllü, Nurettin Beşer, Ömer Yıldız, İmran Kurt Ömürlü, Bülent Bozdoğan PMID: 27282672 PMCID: PMC5331369 doi: 10.5152/AnatolJCardiol.2015.6603 Pages 392 - 396 Objective: The aim of this study was to evaluate the expression levels of cardiac-related circulating microRNAs (miRNAs) in ST-elevation myocardial infarction (STEMI) patients. Methods: This study has a prospective experimental cohort design. A total of 12 consecutive patients with acute chest pain within 12 h admitted to emergency department (STEMI group) and 13 adult patients with normal coronary angiography during the same period were enrolled (control group) in this study. Changes in the expression of miR-122, miR-208, miR-375, miR-22, miR-133b, miR-92b, miR-21, miR-133a, miR-423-5p, miR-27b, miR-30a-3p, miR-17, miR-30d, miR-642, and miR-95 were analyzed using quantitative reverse transcription-polymerase chain reaction. Blood samples were collected before angiography and 24 h after angiography. Data were analyzed using the Statistical Package for the Social Sciences v19. Results: The STEMI group included 12 patients (7 males) with an average age of 56.5±8.3 (range, 44–69) years. The control group included 13 patients (9 males) with an average age of 59±11 (range, 42–80) years. When fold differences were calculated for the miRNA expression values, only miR-30d and miR-423-5p expression levels in STEMI patients showed significant differences in expression levels compared with control patients. The miRNA levels were 2.3-fold higher for miR-30d (p=0.034) and 6.9-fold higher for miR-423-5p (p=0.017). There was no significant correlation between troponin I and miR-30d or miR-423-5p levels (p>0.05). Conclusion: In this study, the expression levels of miRNAs related to cardiac disease were evaluated in peripheral blood. The circulating miR- 423-5p and miR-30d levels in peripheral blood were found to be higher in STEMI cases than in the control group. Further studies should be conducted to evaluate their potential use as biomarkers in STEMI cases. (Anatol J Cardiol 2016; 16; 392-6) |
5. | Myocardial infarction as a thrombotic complication of essential thrombocythemia and polycythemia vera Eva Posfai, Imelda Marton, Zita Borbenyi, Attila Nemes PMID: 27182615 PMCID: PMC5331370 doi: 10.14744/AnatolJCardiol.2015.6125 Pages 397 - 402 Objective: Detailed analyses of clinical characteristics of myocardial infarction (MI) as an essential thrombocythemia (ET)- and polycythemia vera (PV)-related complication have been so far presented mostly as case reports. Therefore, the aim of this retrospective analysis was to evaluate the main cardiological and hematological characteristics for better understanding myocardial complications in ET/PV. Methods: A retrospective analysis was carried out involving 263 patients diagnosed with ET or PV (155/108) between 1998 and 2014. Fourteen patients suffered MI during the hematological follow-up. Their clinical characteristics were compared to 162 patients (97 ET and 65 PV patients) who did not exhibit any major thrombotic complications (MI, stroke/transient ischemic attack, and venous events) before or after hematological diagnosis of ET/PV. Results: Fourteen MI events occurred among the 263 patients (5.3%). Vascular risk factors were found in 92.9% (13/14) of analyzed cases. In all, 71.4% of the MI complications developed within 12 months after the diagnosis of ET/PV. The coronary angiography findings revealed ST-elevation MI in four cases and non-ST-elevation MI in 10. Significant stenosis of coronary arteries requiring percutaneous coronary intervention with a stent implantation was present in seven cases, while three had complex stenoses or previous grafts/stents. All of them had undergone coronary artery bypass graft operations. Conclusion: The results of the present study suggest that early detection and consideration of individual management of vascular risk factors in ET/PV patients are also important. Furthermore, a better theoretic understanding of platelet activation and role of leukocytes in myeloproliferative neoplasm-related thrombosis could open new perspectives in thrombosis prediction and prevention. (Anatol J Cardiol 2016; 16: 397-402) |
EDITORIAL COMMENT | |
6. | Myocardial infarction as a thrombotic complication of myeloproliferative disorders Emmanouil Petrou, Vasiliki Karali PMID: 27282673 PMCID: PMC5331371 doi: 10.14744/AnatolJCardiol.2016.18293 Pages 403 - 404 Abstract |Full Text PDF |
ORIGINAL INVESTIGATION | |
7. | Relationship between metabolic syndrome and epicardial fat tissue thickness in patients with chronic obstructive pulmonary disease Melike Demir, Halit Acet, Halide Kaya, Mahsuk Taylan, Murat Yüksel, Süreyya Yılmaz, Cengizhan Sezgi, Gülistan Karadeniz, Derya Yenibertiz PMID: 27025203 PMCID: PMC5331372 doi: 10.14744/AnatolJCardiol.2016.6566 Pages 405 - 411 Objective: An increase in epicardial fat tissue (EFT) thickness was found to be associated with metabolic syndrome (MS) and ischemic heart disease. MS is a comorbidity of chronic obstructive pulmonary disease (COPD) resulting from the accompanying systemic inflammation. The aim of our study was to investigate the usefulness of EFT thickness to predict MS in COPD patients. Methods: COPD patients admitted to our clinic during January–December 2014 and healthy controls were included in this prospective casecontrol study. Patients with comorbidities, COPD exacerbation, and malignancies were excluded. Patients and controls were compared in terms of anthropometric measurements, MS-related examination and laboratory findings, pulmonary function tests, and EFT thickness. The correlations between EFT thickness and markers of MS in COPD were evaluated using the Student’s t-test and logistic regression analysis. Results: COPD patients and controls were composed of 82 and 84 individuals, respectively. MS was diagnosed in 31 (37.8%) COPD patients. The EFT thickness was significantly higher in COPD patients than in the controls and was also higher in COPD patients with MS than in those without MS (all p<0.001). Each 1-mm increment of EFT raised the risk of MS two-fold (p=0.011, OR=2.08, 95% CI: 1.18–3.68). Increase in triglyceride level (p=0.004, OR=1.02, 95% CI: 1.01–1.03) and reduction in forced vital capacity (p=0.025, OR=0.26, 95% CI: 0.08–0.84) were found to be associated with increased MS risk. The cut-off value for EFT thickness in the prediction of MS in COPD patients was 6.75 mm (sensitivity: 83%, specificity: 65%). Conclusion: EFT thickness is a non-invasive and easily available parameter, which is valuable in the prediction of increased MS risk in COPD patients. Early diagnosis of patients at risk of MS may help to prevent ischemic heart disease in these patients. (Anatol J Cardiol 2016; 16: 405-11) |
8. | Comparison of the Framingham risk and SCORE models in predicting the presence and severity of coronary artery disease considering SYNTAX score Zeki Yüksel Günaydın, Ahmet Karagöz, Osman Bektaş, Ahmet Kaya, Tuncay Kırış, Güney Erdoğan, Turgay Işık, Erkan Ayhan PMID: 26680546 PMCID: PMC5331373 doi: 10.5152/AnatolJCardiol.2015.6317 Pages 412 - 418 Objective: Although various risk stratification models are available and currently being used, the performance of these models in different populations is still controversial. We aimed to investigate the relation between the Framingham and SCORE models and the presence and severity of coronary artery disease, which is detected using the SYNTAX score. Methods: The observational cross-sectional study population consisted of 227 patients with a mean age of 63.3±9.2 years. The patients were classified into low- and high-risk groups in the Framingham and SCORE models separately. Following coronary angiography, the patients were classified into SYNTAX=0 (SYNTAX score 0), low SYNTAX (SYNTAX score 1–22), and high SYNTAX (SYNTAX score>22) groups. The relation between the risk models and SYNTAX score was evaluated by student t test, Mann–Whitney U test or Kruskal–Wallis test and Receiver operating characteristic analysis were used to detect the discrimination ability in the prediction of SYNTAX score>0 and a high SYNTAX score. Results: Both the Framingham and SCORE models were found to be effective in predicting the presence of coronary artery disease, and neither of the two models had superiority over each other [AUC=0.819 (0.767, 0.871) vs. 0.811 (0.757, 0.861), p=0.881]. Furthermore, both models were also effective in predicting the extent and severity of coronary artery disease [AUC=0.724 (0.656, 0.798) vs. 0.730 (0.662, 0.802), p=0.224]. When the subgroups were analyzed, the SCORE model was found to be better in predicting coronary artery disease extent and severity in subgroups of men and diabetics {[AUC=0.737 (0.668, 0.844) vs. 0.665 (0.560, 0.790), p=0.019], [AUC=0.733 (0.684, 0.798) vs. 0.680 (0.654, 0.750) p=0.029], respectively). Conclusion: In addition to their role in predicting cardiovascular events, the use of the Framingham and SCORE models may also have utility in predicting the extent and severity of coronary artery disease. The SCORE risk model has a slightly better performance than the Framingham risk model. (Anatol J Cardiol 2016; 16: 412-8) |
9. | Assessment of the left ventricular systolic function in cardiac syndrome X using speckle tracking echocardiography Jülide Yağmur, Nusret Açıkgöz, Mehmet Cansel, Necip Ermiş, Yasin Karakuş, Ertuğrul Kurtoğlu PMID: 26680547 PMCID: PMC5331374 doi: 10.5152/AnatolJCardiol.2015.6388 Pages 419 - 423 Objective: The aim of this study was to evaluate left ventricular (LV) systolic strain by speckle tracking echocardiography (STE) and real-time three-dimensional echocardiography (3-DE) for the early detection of myocardial dysfunction in patients with cardiac syndrome X (CSX). Methods: We compared 34 patients with CSX (18 females, mean age 47.9±10.0 years) with 41 healthy persons as a control group (23 females, mean age 50.6±9.9 years). Inclusion criteria for CSX were typical angina, a positive exercise ECG stress test, and angiographically documented normal coronary arteries. Exclusion criteria for both groups were hypertension, valvular heart disease, cardiomyopathies, inflammatory diseases, myocarditis, vasculitis, arthropathies, Tietze’s syndrome, gastrointestinal diseases, aortic diseases, hormone replacement therapy, arrhythmias, liver diseases, and alcohol use. All subjects underwent two-dimensional STE and 3-DE to assess resting LV function. STE measures were taken from the basal septum, mid-septum, apical septum, apex, apicolateral, mid-lateral, basal lateral, anteroseptal, anterior, anterolateral, inferolateral, inferior, and inferoseptal walls. Student’s t-test, Mann–Whitney U test, and chi-square test were used to statistically analyze data. Results: LV echo ejection fraction (EF) and systolic wave peak velocity were similar for both groups. Regional mean longitudinal strain (-17.7±2.5% vs. -19.8±1.8%; p<0.0001) was significantly lower in patients with CSX than in healthy control patients. However, regional mean circumferential strain values (-22.0±1.6% vs. -22.2±2.3%; p=0.78) did not differ significantly between the two groups. Conclusion: Significant impairment of LV longitudinal myocardial systolic function was detected with STE in patients with CSX, although normal 3-D EF and tissue Doppler imaging systolic parameters were observed. Arteriosclerosis of small coronary arteries and microvascular dysfunction may affect myocardial longitudinal strain. (Anatol J Cardiol 2016; 16: 419-23) |
10. | Investigation of X-ray permeability of surgical gloves coated with different contrast agents Mustafa Kayan, Selçuk Yaşar, Mustafa Saygın, Ömer Yılmaz, Aykut Recep Aktaş, Fatmanur Kayan, Yasin Türker, Gürsel Çetinkaya PMID: 26680548 PMCID: PMC5331375 doi: 10.5152/AnatolJCardiol.2015.6389 Pages 424 - 427 Objective: We aimed to investigate the effectiveness and radiation protection capability of latex gloves coated with various contrast agents as an alternative to lead gloves. Methods: The following six groups were created to evaluate the permeability of X-ray in this experimental study: lead gloves, two different nonionic contrast media (iopromide 370/100 mg I/mL and iomeprol 400/100 mg I/mL), 10% povidone–iodine (PV–I), 240/240 g/mL barium sulphate and a mixture of equal amounts of all contrast agents. A radiation dose detector was placed in coated latex gloves for each one. The absorption values of radiation from latex gloves coated with various contrast agents were measured and compared with the absorption of radiation from lead gloves. This study was designed as an ‘experimental study’. Results: The mean absorption value of X-ray from lead gloves was 3.0±0.08 µG/s. The mean absorption values of X-ray from latex gloves coated with various contrast agents were 3.7±0.09 µG/s (iopromide 370/100 mg I/mL), 3.6±0.09 µG/s (iomeprol 400/100 mg I/mL), 3.7±0.04 µG/s (PV–I), 3.1±0.07 µG/s (barium sulphate) and 3.8±0.05 µG/s (mixture of all contrast agents). Latex gloves coated with barium sulphate provided the best radiation absorption compared with latex gloves coated with other radiodense contrast agents. Conclusion: Latex gloves coated with barium sulphate may provide protection equivalent to lead gloves. (Anatol J Cardiol 2016; 16: 424-7) |
11. | Comparison of left atrial volume and function in non-dipper versus dipper hypertensives: A real-time three-dimensional echocardiography study Necip Ermiş, Yılmaz Ömür Otlu, Abdülmecit Afşin, Şıho Hidayet, Nusret Açıkgöz, Mehmet Cansel, Jülide Yağmur, M. Cengiz Çolak PMID: 27182617 PMCID: PMC5331376 doi: 10.14744/AnatolJCardiol.2015.6569 Pages 428 - 433 Objective: Non-dipper hypertension is associated with an increased cardiovascular morbidity and mortality. Besides this, the left atrial (LA) size and functions are accepted to be prognostic factors in various cardiovascular diseases. In this study, we aimed to evaluate the effect of nondipper hypertension on LA volume and functions using real-time three-dimensional echocardiography (RT3-DE). Methods: Forty dipper and 52 non-dipper hypertensives enrolled in this prospective cross-sectional study. Patients with any comorbidities that have a potential for causing structural cardiac alterations were excluded. Two-dimensional echocardiography (2-DE) and RT3-DE were performed to assess LA volumes and functions. The statistical tests used in this study were Shapiro–Wilk’s test, Student’s t-test, Mann–Whitney U test, chi-square test, Spearman’s test, and Pearson’s correlation test. Results: LA minimal volume, LA volume before LA contraction, and LA total systolic volume were higher in non-dipper hypertensives than in dipper hypertensives (p<0.001, p=0.003, and p=0.03, respectively). Only, the 2-DE measurements of interventricular septal thickness and E/Em ratio were higher in non-dipper hypertensives (p=0.001 and p=0.03, respectively). There was a moderate correlation between LA minimal volume and LA volume before LA contraction with E/Em (r=0.31, p=0.007 and r=0.32, p=0.005, respectively). Conclusion: Although LA volume and passive LA systolic functions measured by RT3-DE are significantly increased in non-dipper hypertensives, the alterations in active LA systolic functions are not prominent. RT-3DE may be used to define LA volume and function alterations in conditions that have capabilities of adverse cardiac remodeling such as systemic hypertension. (Anatol J Cardiol 2016; 16: 428-33) |
12. | Evaluation of torsion and twist mechanics of the left ventricle in patients with systemic lupus erythematosus Mustafa Bulut, Rezzan Deniz Acar, Şencan Acar, Serdar Fidan, Mahmut Yesin, Servet İzci, Süleyman Cağan Efe, Hakan Çakır PMID: 26680549 PMCID: PMC5331377 doi: 10.5152/AnatolJCardiol.2015.6324 Pages 434 - 439 Objective: Myocardial involvement in systemic lupus erythematosus (SLE) has great importance. The aim of this study is to evaluate the rotation and twisting mechanics of the left ventricle (LV) in patients with SLE. Methods: Forty-three patients fulfilled at least four of the American College of Rheumatology criteria for SLE and 30 individuals as controls were included in the study. SLE disease activity was assessed using the SELENA–SLEDAI score. Echocardiography was performed for all subjects. The patients fulfilled at least four of the American College of Rheumatology criteria for SLE were enrolled in the study. SLE disease activity was assessed using the SELENA-SLEDAI score. Echocardiography was performed for all individuals.Comparisons between groups were made using independent samples t-test with the standard statistical software (SPSS, version 15.0; SPSS Inc., Chicago, IL, USA). Each image was digitally stored for offline analysis. Measurement of global strain assessed by 17-segment model and rotational parameters were performed. LV ejection fraction was calculated by the biplane Simpson’s method. Comparisons between groups were made using the independent samples t-test with the standard statistical software. A p value of 0.05 was considered statistically significant. Results: The values of mean global longitudinal strain, basal global circumferential strain (GCS), mean basal radial strain, and apical GCS were significantly lower in SLE patients. The difference between basal rotation, apical rotation, twist of the LV, and torsion of the LV in the SLE patients and controls were not significant (8.8±5.5 vs. 10.6±5.8, p=0.183;-4.7±3.0 vs. -4.8±3.2, p=0.947; 11.7±6.4 vs. 13.2±6.4, p=0.366; and 1.8±0.8 vs. 1.9±2.3, p=0.725, respectively). Although there was not any significant relationship between SELENA–SLEDAI score and myocardial strain analyses of the LV, the basal rotation and the torsion of the LV were lower in patients with SLE having a SLEDAI score of ≥17 (p=0.024 for basal rotation and p=0.032 for torsion). Conclusion: The number of segmental and global strain analyses were decreased in SLE patients with globally normal LVEF. The twist and torsion mechanics of the LV were preserved according to the control group, and the left ventricular torsion and basal rotation were found to be significantly decreased in those with an activity score of ≥17. (Anatol J Cardiol 2016; 16: 434-9) |
13. | Evaluation of atherosclerosis after cessation of cabergoline therapy in patients with prolactinoma Berçem Ayçiçek Doğan, Ayşe Arduç, Mazhar Müslüm Tuna, Narin Imga Nasıroğlu, Serhat Işık, Dilek Berker, Serdar Güler PMID: 26680550 PMCID: PMC5331378 doi: 10.5152/AnatolJCardiol.2015.6416 Pages 440 - 447 Objective: The aim of the study was to determine whether atherosclerotic risk markers exist at the moment and after withdrawal of cabergoline (CAB) therapy in patients who had taken a suitable dose of CAB therapy for a suitable period of time before cessation of CAB. Methods: This study was designed as prospective cross-sectional. Out of a total of 115 patients with prolactinoma, 42 non-obese women with microprolactinoma, who met the Pituitary Society criteria (2006) for the withdrawal of long-term CAB therapy, and 30 healthy patients participated in our study. The number of patients excluded from the study were as follows: 34 patients with tumor shrinkage of less than 50%; 10 who received DA treatments for less than 2 years; 9 who were treated with bromocriptine; and 20 who had diabetes mellitus, hypertension, hyperlipidemia, obesity, renal disease, coronary arterial disease, or were tobacco smokers. The patients were evaluated for anthropometric, metabolic, and inflammatory parameters at the time of cessation of CAB therapy and at the 3rd and 12th months after the withdrawal of CAB therapy. Endothelial dysfunction was determined by flow-mediated dilation (FMD) of the brachial artery and carotid intima media thickness (IMT), which were assessed by high resolution ultrasonography (USG) by the same practitioner. Results: At the moment of cessation of CAB therapy, the FMD percentage in patients with prolactinoma was worse than that in healthy controls (p=0.0029). After the withdrawal of CAB treatment, fibrinogen (p=0.036), mean platelet volume (MPV) (p<0.001), carotid IMT (p=0.041), and high-density lipoprotein cholesterol (HDL C) (p=0.048) were worse in the relapse patients than those in the remission patients. Furthermore, only MPV values were found to be significantly related to a relapse of hyperprolactinemia among all atherosclerotic risk markers [area under the curve: 0.830 (95% CI 0.685–0.974) (p<0.001)]. Conclusion: Unfavorable cardiovascular risk profiles are a problem for patients with prolactinoma during cessation and after CAB withdrawal. (Anatol J Cardiol 2016; 16: 440-7) |
PUBLICATION ETHICS | |
14. | An aspect to the publication ethics subject in the open access online journals F. Suna Kıraç PMID: 27282674 PMCID: PMC5331379 doi: 10.14744/AnatolJCardiol.2016.7293 Pages 448 - 449 Abstract |Full Text PDF |
CASE REPORT | |
15. | Successful sequential drug eluting balloon angioplasty to chronic total occluded popliteal artery in a patient with thromboangitis obliterans by PCR Fehmi Kaçmaz, Adnan Kaya, Aysel Yazıcı PMID: 27282675 PMCID: PMC5331380 doi: 10.14744/AnatolJCardiol.2016.6979 Pages 450 - 451 Abstract |Full Text PDF |
LETTER TO THE EDITOR | |
16. | Value of neutrophil-to-lymphocyte ratio and its combination with GRACE risk score in predicting PCI outcomes in acute coronary syndrome Can Ramazan Öncel PMID: 27282676 PMCID: PMC5331381 doi: 10.14744/AnatolJCardiol.2016.6989 Page 452 Abstract |Full Text PDF |
17. | Current studies about the energy drinks may not simulate the real life Mustafa Aparcı, Ömer Uz, Zafer Işılak PMID: 27282677 PMCID: PMC5331382 doi: 10.14744/AnatolJCardiol.2016.7106 Page 453 Abstract |Full Text PDF |
18. | Nebivolol compared with metoprolol for erectile function in males undergoing coronary artery bypass graft Levent Cerit PMID: 27282679 PMCID: PMC5331384 doi: 10.14744/AnatolJCardiol.2016.7121 Page 454 Abstract |Full Text PDF |
19. | Author`s Reply Shokoufeh Hajsadeghi PMID: 27282678 PMCID: PMC5331383 Page 454 Abstract |Full Text PDF |
20. | Author`s Reply Mustafa Karalar, Mustafa Aldemir PMID: 27282680 PMCID: PMC5331385 Page 455 Abstract |Full Text PDF |
21. | Cardiac problem because of Zika virus infection: a possibility Beuy Joob, Viroj Wiwanitkit PMID: 27282681 PMCID: PMC5331386 doi: 10.14744/AnatolJCardiol.2016.7140 Pages 455 - 456 Abstract |Full Text PDF |
MISCELLANEOUS | |
22. | Conference Report: The 2nd Symposium of sudden cardiac arrest survival Mutlu Vural, Abdullah Olgun PMID: 27282682 PMCID: PMC5331387 doi: 10.14744/AnatolJCardiol.2016.7292 Pages 457 - 458 Abstract |Full Text PDF | Video |
E-PAGE ORIGINAL IMAGES | |
23. | Cardiac metastasis of synovial sarcoma presenting with superior vena cava syndrome Nil Özyüncü, Nazlı Turan, Demet Menekşe Gerede, Evren Özçınar, Sadi Güleç, Sibel Perçinel, Çetin Erol PMID: 27282684 PMCID: PMC5331388 doi: 10.14744/AnatolJCardiol.2016.7126 Page E11 Abstract |Full Text PDF | Video |
24. | Rheumatic involvement of the cleft mitral valve Begüm Uygur, Hale Ünal Aksu, Abdurrahman Eksik PMID: 27282683 PMCID: PMC5331389 doi: 10.14744/AnatolJCardiol.2016.7148 Page E12 Abstract |Full Text PDF | Video |
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