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Volume : 21 Issue : 6 Year : 2021
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The Anatolian Journal of Cardiology - Anatol J Cardiol: 21 (6)
Volume: 21  Issue: 6 - June 2019
1.Troponins, WATCMAN, and much more
Çetin Erol
PMID: 31142727  doi: 10.14744/AnatolJCardiol.2019.6  Page 295
Abstract | Full Text PDF

2.Knowledge and experience of cardiopulmonary resuscitation among cardiologists in clinical practice: A multicenter cross-sectional study
Veysel Oktay, ilknur Calpar Cirali, Onur Baydar, Vedat Sansoy
PMID: 31142720  doi: 10.14744/AnatolJCardiol.2019.53383  Pages 296 - 304
Objective: This study aimed to investigate the theoretical knowledge and clinical experience of cardiopulmonary resuscitation (CPR) among Turkish cardiologists according to the recommendations of the 2015 European Resuscitation Council (ERC) guidelines.
Methods: A total of 120 cardiologists from 14 different medical centers (six university and eight research-education hospitals) in İstanbul were included in the study. The questionnaire consisting of 29 open-ended and multiple choice questions on CPR was used and validated based on the ERC guidelines published in 2015. The percentage of correct answers was calculated for each participant.
Results: Of the 120 cardiologists included in this study, 108 (90%) accepted the participation, and the median percentage of correct answers for theoretical questions was 53% (38-72). The percentage of correct answers for interventional cardiologists (48%, n=52) was significantly higher [60% (50–66) vs. 46% (38-52), p<0.001]. Regarding the type of medical centers, no statictical difference was found in terms of theoretical knowledge on CPR [57% (50-72) university hospitals vs. 49% (41-57) research-education hospitals, p=0.160). Peri-arrest transthoracic echocardiography was used in 71% of cases. The ratio of participants who had received an advanced cardiac life support course in the preceding year was only 19% (n=20), and those participants had a significantly higher score regarding the CPR theoretical knowledge questions [68% (54-70) vs. 46% (38-51), p<0.001].
Conclusion: The theoretical knowledge of cardiologists on CPR is not satisfactory according to the 2015 ERC guidelines. An increased frequency of CPR training courses may improve this result.

3.The concentration of interleukin-33 in heart failure with reduced ejection fraction
Oliwia Anna Segiet, Ewa Romuk, Ewa Nowalany-Kozielska, Celina Wojciechowska, Adam Piecuch, Romuald Wojnicz
PMID: 31142723  doi: 10.14744/AnatolJCardiol.2019.64614  Pages 305 - 313
Objective: Despite several improvements in the management of heart failure (HF), it is still an incurable and a progressive disease. Several trials demonstrated that the process of inflammation may be responsible for initiation and progression of HF. The aim of the present study was to investigate the role of interleukin-33 (IL-33) in the pathogenesis of HF and to assess whether disease etiology and course of the disease affect the expression of cytokines.
Methods: The study included 155 (106 male and 49 female) patients with systolic HF with a mean left ventricle ejection fraction of 32.13±12.8% and 60 (36 male and 24 female) healthy individuals. IL-33 concentrations were evaluated using enzyme-linked immunosorbent assay.
Results: The concentration of IL-33 was statistically significantly lower in patients with HF than in healthy subjects, 16.91 (0–81.00) pg/mL and 92.51 (33.61–439.61) pg/mL, respectively. Patients with HF with ischemic etiology had lower concentration of IL-33 (10.75 pg/mL) than subjects with HF with non-ischemic etiology (21.05 pg/mL). Patients with stable HF (10.46 pg/mL) had lower IL-33 levels than those with unstable HF (19.02 pg/mL).
Conclusion: The concentrations of IL-33 were lower in patients with HF than in healthy controls, which may play an important role of above cytokine in HF development and progression. In addition, interleukin concentrations varied depending on the etiology and severity of the course of the disease.

4.Experience of left atrial appendage occlusion with the WATCHMAN device in Chinese patients
Zhengqin Zhai, Min Tang, Xi Su, Huimin Chu, Weijian Huang, Jie Zeng, Jianan Wang, Pihua Fang, Xiaomeng Yin, Genshan Ma, Shuang Zhao, Shu Zhang
PMID: 31142725  doi: 10.14744/AnatolJCardiol.2019.75435  Pages 314 - 321
Objective: Little is known about left atrial appendage occlusion (LAAO) with WATCHMAN device in patients with atrial fibrillation (AF) in China. The aim of the present study was to evaluate the acute procedural performance and complication rate of LAAO procedures and patient selection in China.
Methods: A total of 658 consecutive Chinese patients who were referred to receive LAAO procedures with the WATCHMAN device between 2014 and 2017 were retrospectively included in the study. Patients were divided into four groups according to the year of procedures: Group 2014, Group 2015, Group 2016, and Group 2017. The procedural success, complication rates, and characteristics of Chinese patients, as well as the trends of patients’ selection and management, were analyzed.
Results: The average age of the patients was 67.7±9.2 years, the CHA2DS2-VASc score was 3.7±1.6, and the HAS-BLED score was 2.5±1.1. Both scores of patients in different years show obvious increasing trends (r=0.126, p=0.001 and r=0.145, p<0.001, respectively). Indications for LAAO included increased bleeding risk (45.6%), recent bleeding under oral anticoagulation (OAC) (9.0%), and non-compliance with OAC (51.4%). The implantation was successful in 643 (97.7%) patients, with a procedural complication rate of 0.6%. Approximately 80.1% of the patients received OAC after LAAO.
Conclusion: In China, LAAO with WATCHMAN devices in patients with AF can be performed successfully with a low complication rate. Most of the target population had increased bleeding risk or non-compliance for OAC as indications and received OAC for antithrombotic therapy after the procedure.

5.Risk assessment and survival of patients with pulmonary hypertension: Multicenter experience in Turkey
Yalın Tolga Yaylalı, Ibrahim Başarıcı, Burçak Kılıçkıran Avcı, Murat Meriç, Ümit Yaşar Sinan, Hande Şenol, Mehmet Serdar Küçükoğlu, Zeki Öngen
PMID: 31142721  doi: 10.14744/AnatolJCardiol.2019.53498  Pages 322 - 330
Objective: Risk stratification continues to evolve in pulmonary arterial hypertension (PAH). Our aim was to further confirm the risk assessment strategy in our cohort and to determine the most reliable model.
Methods: We enrolled incident patients with idiopathic PAH (IPAH), heritable, drug-induced, congenital heart disease (CHD), connective tissue diseases (CTD) subsets, and chronic thromboembolic pulmonary hypertension (CTEPH) from January 2008 to February 2018. Data from the baseline and subsequent follow-ups within 1 year of diagnosis were included. An abbreviated risk assessment strategy was applied using the following variables: functional class (FC), 6-minute walk distance (6 MWD), N-terminal pro–brain natriuretic peptide (NT-proBNP) or BNP, right atrial (RA) area, pericardial effusion, the mean RA pressure, cardiac index, and mixed venous oxygen saturation. Three different methods were applied to categorize patients.
Results: A total of 189 subjects (46±17 years, 23% male) were included. Sixty-one patients had died. The survival differed significantly between the risk groups both at diagnosis and during the follow-up. Patients with a low-risk profile had a better survival rate. An abbreviated risk assessment tool predicted mortality at early follow-up in the entire group and CHD, CTD subsets, and CTEPH, separately. An overall mortality among risk categories was significantly different according to each categorization method. The most reliable model comprised FC, 6 MWD, NT pro-BNP/BNP, and the RA area at the follow-up.
Conclusion: The abbreviated risk assessment tool may be valid for the PAH subsets and CTEPH. Echocardiographic variables do matter. A model comprising FC, 6 MWD, NT pro-BNP/BNP, and the RA area at the follow-up could be useful for better prognostication.

6.Turkish Society of Cardiology consensus report on the rational use of cardiac troponins in daily practice
Kaan Okyay, Beste Ozben Sadıc, Asife Sahinarslan, Murtaza Emre Durakoglugil, Can Yucel Karabay, Semiha Emel Eryüksel, Özlem Gulbahar, Abdullah Tekin, Reviewers:, Aylin Yıldırır, Bülent Görenek, Oğuz Yavuzgil, Ali Serdar Fak
PMID: 31073114  doi: 10.14744/AnatolJCardiol.2019.42247  Pages 331 - 344
Abstract | Full Text PDF

7.Vocal cord paralysis after transcatheter patent ductus arteriosus closure with AMPLATZERTM Vascular Plug II
Ibrahim Cansaran Tanidir, Bekir Yukcu, Erkut Ozturk, Alper Guzeltas
PMID: 31142726  doi: 10.14744/AnatolJCardiol.2019.88393  Pages 345 - 346
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8.An extreme case of vasospastic angina mimicking acute STEMI: Severe threevessel disease with critical stenoses
Çağlar Kaya, Servet Altay
PMID: 31142724  doi: 10.14744/AnatolJCardiol.2019.74171  Pages 347 - 349
Abstract | Full Text PDF

9.Left ventricular global longitudinal strain rate is influenced by stable coronary artery disease
Yusuf Ziya Şener, Metin Okşul, Vedat Hekimsoy
PMID: 31142719  doi: 10.14744/AnatolJCardiol.2019.36525  Page 350
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10.Author`s Reply
Mustafa Doğduş, Salih Kılıç, Ertan Vuruşkan
Pages 350 - 351
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11.Treatment for acute type B intramural hematoma and patent ductus arteriosus in an adult using a covered stent
Qian Tong, Jing Wang, Xinyu Yang, Dianbo Cao
PMID: 31142718  doi: 10.14744/AnatolJCardiol.2019.23780  Pages E13 - E14
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12.An unusual cause of pulmonary hypertension; partial anomalous pulmonary venous return to coronary sinus detected on transesophageal echocardiography
Emrah Erdoğan, Murat Cap, Süleyman Efe
PMID: 31142722  doi: 10.14744/AnatolJCardiol.2019.60734  Pages E14 - E15
Abstract | Full Text PDF | Video