ISSN 2149-2263 | E-ISSN 2149-2271
The Anatolian Journal of Cardiology
Mean systolic annular velocity and strain score index: new and non-invasive parameters for the evaluation of acute myocardial infarction patients [Anatol J Cardiol]
Anatol J Cardiol. 2010; 10(3): 239-246 | DOI: 10.5152/akd.2010.064

Mean systolic annular velocity and strain score index: new and non-invasive parameters for the evaluation of acute myocardial infarction patients

Ergün Barış1, Necla Özer2, Hakan Aksoy3, Onur Sinan Deveci4, Erol Tülümen3, Sercan Okutucu3, Hikmet Yorgun7, Enver Atalar8, Serdar Aksöyek8, Ferhan Özmen8, Kenan Övünç8, Hilmi Özkutlu8, Sırrı Kes1
1Hacettepe Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Ankara, Türkiye
2Hacettepe Üniversitesi Tıp Fakültesi Kardiyoloji Anabilim Dalı, Ankara, Türkiye
3Department of Cardiology, Faculty of Medicine, University of Hacettepe, Ankara Turkey
4Department of Cardiology, Gülhane Military Medical Academy, Haydarpaşa Hospital, İstanbul-Turkey
5Department of Cardiology, Faculty of Medicine, University of Hacettepe, Ankara Turkey
6Department of Cardiology, Faculty of Medicine, University of Hacettepe, Ankara Turkey
7Cardiology Clinic, Develi State Hospital, Kayseri-Turkey
8Hacettepe Üniversitesi, Tıp Fakültesi Kardiyoloji Anabilim Dalı, Ankara, Türkiye

Objective: To evaluate the diagnostic value of mean annular velocity (MAV) and strain score index (SSI) for determination of the left ventricular systolic dysfunction in patients with first acute myocardial infarction (AMI). Methods: Seventy-one patients (55 male, mean age: 59±12 years) with first acute ST-elevation myocardial infarction and 30 healthy subjects were included in this cross-sectional and observational study. Echocardiography with tissue Doppler and strain analysis was performed during initial hospital admission. Peak systolic myocardial velocities were recorded from 4 different sites on the mitral annulus. A MAV value was calculated and the peak systolic strain values of 12 segments were measured and a mean SSI was calculated. ROC curve analysis was used in order to determine cut-off values for MAV and SSI. Results: The patients with AMI had a significantly reduced MAV compared with healthy subjects (5.52±1.78 cm/s vs 9.80±1.13 cm/s, p<0.001). In ROC analysis, a cut-off value of 8.41 cm/s (AUC 0.915, 95%CI 0.887-0.952, p<0.001) for MAV differentiated AMI patients from controls with 97.2% sensitivity and 93.3% specificity. The patients with AMI have also decreased SSI (11.23±2.83 vs 19.11±2.05, p<0.001). A cut-off value of 15.35% differentiated AMI patients from controls with 94.4% sensitivity and 100% specificity (ROC AUC 0.945, 95%CI 0.901-0.972, p<0.001). There was a good correlation between left ventricular EF and MAV (r=0.73, p<0.001) and SSI (r=0.66, p<0.001). Conclusion: The patients with first myocardial infarction have decreased mean systolic annular velocity and mean systolic strain score index.

Keywords: Acute myocardial infarction, tissue Doppler, strain echocardiography, diagnostic value of tests, logistic regression analysis, diagnostic value of tests

Ergün Barış, Necla Özer, Hakan Aksoy, Onur Sinan Deveci, Erol Tülümen, Sercan Okutucu, Hikmet Yorgun, Enver Atalar, Serdar Aksöyek, Ferhan Özmen, Kenan Övünç, Hilmi Özkutlu, Sırrı Kes. Mean systolic annular velocity and strain score index: new and non-invasive parameters for the evaluation of acute myocardial infarction patients. Anatol J Cardiol. 2010; 10(3): 239-246
Manuscript Language: English


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