Objective: The number of percutaneous coronary interventions (PCI) is increasing. There is limited outcome data on patients with a his- tory of PCI and subsequently required surgical revascularization. Methods: Overall 611 patients who survived 30 days after coronary artery bypass graft surgery (CABG) between 2001 and 2005 were eva- luated. Mean follow-up was 29.4 ± 11.3 months and 45% were female. The effect of preoperative PCI as a risk factor for symptom recur- rence and adverse cardiovascular events and mortality was determined. Results: Preoperative PCI was an independent risk factor for symptom recurrence (p<0.0001), combined adverse cardiac events (p<0.0001) and slightly increased overall mortality (p<0.04). Comparison of patients with and without a prior PCI showed that former had significantly worse outcomes compared to the latter. Patients with history of at least one restenosis following a PCI developed sig- nificantly more adverse end points (p<0.0001). Conclusion: In this study, patients with previous PCI were more likely to develop symptom recurrence and adverse cardiovascular events following CABG. This difference was more pronounced in patients who had at least one recurrent stenosis after a PCI.