Rationale, Design, and Methodology of the MORCOR-TURK Trial: Predictors of In-hospital MORtality in CORonary Care Patients in Turkey
1Department of Cardiology, Kütahya Evliya Çelebi Training and Research Hospital, Kütahya, Turkey
2Department of Cardiology, Faculty of Medicine, Afyonkarahisar Science of Health University, Afyonkarahisar, Turkey
3Department of Cardiology, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize, Turkey
4Department of Cardiology, Faculty of Medicine, Medeniyet University, İstanbul, Turkey
5Department of Cardiology, Cerrahpaşa Faculty of Medicine, İstanbul University, İstanbul, Turkey
6Department of Cardiology, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey
7Department of Cardiology, Edirne Sultan 1. Murat State Hospital, Edirne, Turkey
8Department of Cardiology, Ahi Evren Training and Research Hospital, Trabzon, Turkey
9Department of Cardiology, Yalova State Hospital, Yalova, Turkey
10Department of Cardiology, Private Medical Park Hospital, Antalya, Turkey
11Department of Cardiology, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey
12Department of Cardiology, Bağcılar Training and Research Hospital, İstanbul, Turkey
13Department of Cardiology, Faculty of Medicine, Pamukkale University, Denizli, Turkey
14Department of Cardiology, Isparta City Hospital, Isparta, Turkey
15Department of Cardiology, Faculty of Medicine, Harran University, Şanlıurfa, Turkey
16Department of Cardiology, Faculty of Medicine, Ordu University, Ordu, Turkey
17Department of Cardiology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey
18Department of Cardiology, Faculty of Medicine, Van Yüzüncü Yıl University, Van, Turkey
19Department of Cardiology, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey
20Department of Cardiology, Faculty of Medicine, Gaziosmanpaşa University, Tokat, Turkey
21Department of Cardiology, Tekirdağ City Hospital, Tekirdağ, Turkey
22Department of Cardiology, Faculty of Medicine, İnönü University, Malatya, Turkey
23Department of Cardiology, Keşan State Hospital, Edirne, Turkey
24Department of Cardiology, Faculty of Medicine, Selçuk University, Konya, Turkey
Anatol J Cardiol 2023; 27(5): 258-265 PubMed ID: 37119186 PMCID: 10160834 DOI: 10.14744/AnatolJCardiol.2022.2824
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Abstract

Background: Coronary care units are sophisticated clinics established to reduce deaths due to acute cardiovascular events. Current data on coronary care unit mortality rates and predictors of mortality in Turkey are very limited. The MORtality predictors in CORonary care units in TURKey (MORCOR-TURK) trial was designed to provide information on the mortality rates and predictors in patients followed in coronary care units in Turkey.

Methods: The MORCOR-TURK trial will be a national, observational, multicenter, and noninterventional study conducted in Turkey. The study population will include coronary care unit patients from 50 centers selected from all regions in Turkey. All consecutive patients admitted to coronary care units with cardiovascular diagnoses between 1 and 30 September 2022 will be prospectively enrolled. All data will be collected at one point in time, and the current clinical practice will be evaluated (ClinicalTrials.gov number NCT05296694).

In the first step of the study, admission diagnoses, demographic characteristics, basic clinical and laboratory data, and in-hospital management will be assessed. At the end of the first step, the predictors and rates of in-hospital mortality will be documented. The second step will be in cohort design, and discharged patients will be followed up till 1 year. Predictors of short- and long-term mortality will be assessed. Moreover, a new coronary care unit mortality score will be generated with data acquired from this cohort.

Results: The short-term outcomes of the study are planned to be shared by early 2023.

Conclusion: The MORCOR-TURK trial will be the largest and most comprehensive study in Turkey evaluating the rates and predictors of in-hospital mortality of patients admitted to coronary care units.