, Meral Kayıkçıoğlu 2
, Mustafa Kılıçkap 3
, Can Baba Arın 4
, Ibrahim Halil Kurt 5
, Ibrahim Aktaş 6
, Yılmaz Güneş 7
, Eyüp Özkan 8
, Taner Şen 9
, Orhan Ince 10
, Ender Örnek 11
, Ramazan Asoğlu 12
, Nesim Aladağ 13
, Utku Zeybey 14
, Ümit Yaşar Sinan 15
, Muhammet Dural 16
, Haşim Tüner 17
, Arda Doğan 18
, Mustafa Yenerçağ 19
, Mehmet Akboğa 20
, Onur Sinan Deveci 21
, Mustafa Umut Somuncu 22
2Department of Cardiology, Faculty of Medicine, Ege University; İzmir-Turkey
3Department of Cardiology, Faculty of Medicine, Ankara University; Ankara-Turkey
4Department of Cardiology, Health Science University, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Center, Training and Research Hospital; İstanbul-Turkey
5Department of Cardiology, Health Science University, Adana City Training and Research Hospital; Adana-Turkey
6Department of Cardiology, Health Science University, Malatya Training and Research Hospital; Malatya-Turkey
7Department of Cardiology, Faculty of Medicine, Abant İzzet Baysal University; Bolu-Turkey
8Department of Cardiology, Health Science University, Kayseri City Training and Research Hospital; Kayseri-Turkey
9Department of Cardiology, Faculty of Medicine, Kütahya Health Science University; Kütahya-Turkey
10Department of Cardiology, Health Science University, Bağcılar Training and Research Hospital; İstanbul-Turkey
11Department of Cardiology, Health Science University, Ankara City Training and Research Hospital
12Department of Cardiology, Faculty of Medicine, Adıyaman University, Adıyaman Training and Research Hospital; Adıyaman-Turkey
13Department of Cardiology, Health Science University, Van Training and Research Hospital; Van-Turkey
14Department of Cardiology, Faculty of Medicine, Trakya University; Edirne-Turkey
15Department of Cardiology, Faculty of Medicine, İstanbul University; İstanbul-Turkey
16Department of Cardiology, Faculty of Medicine, Osmangazi University; Eskişehir-Turkey
17Department of Cardiology, Faculty of Medicine, Yüzüncü Yıl University; Van-Turkey
18Department of Cardiology, Health Science University, İstanbul Mehmet Akif Ersoy Thoracic and Cardiovasculer Surgery Center Training and Research Hospital; İstanbul-Turkey
19Department of Cardiology, Health Science University, Samsun Training and Research Hospital; Samsun-Turkey
20Ankara Gazi University and, Ankara City Training and Research Hospital; Ankara-Turkey
21Department of Cardiology, Faculty of Medicine, Çukurova University; Adana-Turkey
22Department of Cardiology, Faculty of Medicine, Bülent Ecevit University; Zonguldak-Turkey
Abstract
Objective: The TURKMI registry is designed to provide insight into the characteristics, management from symptom onset to hospital discharge, and outcome of patients with acute myocardial infarction (MI) in Turkey. We report the baseline and clinical characteristics of the TURKMI population.
Methods: The TURKMI study is a nation-wide registry that was conducted in 50 centers capable of percutaneous coronary intervention selected from each EuroStat NUTS region in Turkey according to population sampling weight, prioritized by the number of hospitals in each region. All consecutive patients with acute MI admitted to coronary care units within 48 hours of symptom onset were prospectively enrolled during a predefined 2-week period between November 1, 2018 and November 16, 2018.
Results: A total of 1930 consecutive patients (mean age, 62.0±13.2 years; 26.1% female) with a diagnosis of acute MI were prospectively enrolled. More than half of the patients were diagnosed with non-ST elevation MI (61.9%), and 38.1% were diagnosed with ST elevation MI. Coronary angiography was performed in 93.7% and, percutaneous coronary intervention was performed in 73.2% of the study population. Fibrinolytic therapy was administered to 13 patients (0.018%). Aspirin was prescribed in 99.3% of the patients, and 94% were on dual antiplatelet therapy at the time of discharge. Beta blockers were prescribed in 85.0%, anti-lipid drugs in 96.3%, angiotensin converting enzyme inhibitors in 58.4%, and angiotensin receptor blockers in 7.9%. Comparison with European countries revealed that TURKMI patients experienced MI at younger ages compared with patients in France, Switzerland, and the United Kingdom. The most prevalent risk factors in the TURKMI population were hypercholesterolemia (60.2%), hypertension (49.5%), smoking (48.8%), and diabetes (37.9%).
Conclusion: The nation-wide TURKMI registry revealed that hypercholesterolemia, hypertension, and smoking were the most prevalent risk factors. TURKMI patients were younger compared with patients in European Countries. The TURKMI registry also confirmed that current treatment guidelines are largely adopted into clinical cardiology practice in Turkey in terms of antiplatelet, anti-ischemic, and anti-lipid therapy.