Functional Coronary Collateral Circulation in Severe Aortic Stenosis with the Absence of Coronary Artery Disease
1Department of Cardiovascular Medicine, Ankara Etlik Training and Research Hospital, Ankara, Türkiye
2Department of Cardiovascular Medicine, Ankara University Faculty of Medicine, Ankara, Türkiye
Anatol J Cardiol 2024; 28(1): 5001-5002 PubMed ID: 38167797 PMCID: 10796242 DOI: 10.14744/AnatolJCardiol.2023.3687
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CONTENT

The coronary collateral flow remains a highly investigated issue in cardiology. We describe a 43-year-old male who presented with functional collateral flow between normal coronary arteries as a result of severe aortic stenosis.

He had been experiencing exertional dyspnea and angina pectoris for 4 months. We performed transthoracic echocardiography, which revealed a calcified bicuspid aortic valve with severe stenosis. A maximum gradient of 77 mm Hg was measured on the aortic valve, with a mean gradient of 51 mm Hg. The aortic valve diameter was calculated as 0.7 cm2 using a continuity equation. Based on these findings, we recommended aortic valve replacement surgery. Preoperative coronary angiography revealed the functional collateral circulation within the normal coronary arteries. There was a grade 3 collateral circulation from the circumflex artery (Cx) to the right coronary artery (RCA) in the left anterior oblique (LAO), the right anterior oblique (RAO), as well as anterior–posterior projections (Figure 1) (Videos 1, 2). Additionally, LAO caudal and cranial projections of RCA indicated the presence of grade 3 collateral arteries from RCA to Cx (Figure 2).

Coronary collateral circulation plays a critical role in coronary artery occlusions. It may also occur in the absence of coronary artery disease.

Several studies have shown that left ventricular hypertrophy can positively influence the state of intercoronary connections. Particularly, left ventricular hypertrophy due to severe aortic valve stenosis may lead to increases in myocardial oxygen demand and coronary artery compression. Consequently, these conditions may contribute to myocardial ischemia and subsequent coronary collateral formation, as observed in our patient.

Footnotes

Informed Consent: An informed consent was obtained from the patient.

Declaration of Interests: The authors have no conflict of interest to declare.

Video 1: The coronary collateral artery from circumflex artery to the normal right coronary artery is visible in the left anterior oblique cranial projection.

Video 2: A prominent grade 3 coronary collateral circulation was visible from the distal RCA to the CX coronary artery.