, Ümit Yaşar Sinan 2
, Emre Aruğaslan 3
, Mustafa Kurşun 4
, Ali Çoner 5
, Özlem Özcan Çelebi 6
, Cengiz Öztürk 7
, Onur Dalgıç 8
, Ebru Ipek Türkoğlu 9
, Hatice Soner Kemal 10
, Emine Gazi 11
, Cihan Altın 12
, Mehdi Zoghi 13
2Department of Cardiology, İstanbul University Institute of Cardiology; İstanbul-Turkey
3Department of Cardiology, Sinop Atatürk State Hospital; Sinop-Turkey
4Department of Cardiology, İzmir Tepecik Training and Research Hospital; İzmir-Turkey
5Department of Cardiology, Başkent University Alanya Hospital; Antalya-Turkey
6Department of Cardiology, Turkey Yüksek İhtisas Training and Research Hospital; Ankara-Turkey
7Department of Cardiology, Gülhane Training and Research Hospital; Ankara-Turkey
8Department of Cardiology, İzmir Karşıyaka State Hospital; İzmir-Turkey
9Department of Cardiology, İzmir Kemalpaşa State Hospital; İzmir-Turkey
10Department of Cardiology, Faculty of Medicine, Near East University; Kyrenia-Cyprus
11Department of Cardiology, Faculty of Medicine, Çanakkale Onsekiz Mart University; Çanakkale-Turkey
12Department of Cardiology, Başkent University İzmir Hospital, İzmir-Turkey
13Department of Cardiology, Faculty of Medicine, Ege University; İzmir-Turkey
Abstract
Objective: Atrial fibrillation (AF) and heart failure (HF) are common cardiovascular diseases. The impact of AF on in-hospital outcomes in acute decompensated heart failure (ADHF) is controversial. The aim of this study is to determine the prevalence of AF among hospitalized patients with ADHF and describe the clinical characteristics and in-hospital outcomes of these patients with and without AF.
Methods: We examined the multicenter, observational data from the real-life data of hospitalized patients with HF: Journey HF-TR study in Turkey that studied the clinical characteristics and in-hospital outcomes of hospitalized patients with ADHF between September 2015 and September 2016.
Results: Of the 1,606 patients hospitalized with ADHF, 626 (39%) had a history of AF or developed new-onset AF during hospitalization. The patients with AF were older (71±12 vs. 65±13 years; p<0.001) and more likely to have a history of hypertension, valvular heart disease, and stroke. The AF patients were less likely to have coronary artery disease and diabetes. In-hospital adverse event rates and length of in-hospital stay were similar in ADHF patients, both with and without AF. In-hospital all-cause mortality rate was higher in patients with AF than in patients without AF, although the difference was not statistically significant (8.9% vs. 6.8%; p=0.121).
Conclusion: AF has been found in more than one-third of the patients hospitalized with ADHF, and it has varied clinical features and comorbidities. The presence of AF is not associated with increased adverse events or all-cause mortality during the hospitalization time.