ISSN 2149-2263 | E-ISSN 2149-2271
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Outcomes of Ozaki Procedure/Aortic Valve Neocuspidization for Aortic Valve Diseases: A Systematic Review [Anatol J Cardiol]
Anatol J Cardiol. 2023; 27(11): 619-627 | DOI: 10.14744/AnatolJCardiol.2023.3477

Outcomes of Ozaki Procedure/Aortic Valve Neocuspidization for Aortic Valve Diseases: A Systematic Review

Samson S. Badalyan1, Syune V. Markosyan2, Alisher M. Ismailbaev3, Andleeb Asghar4, Aniq Ur Rehman5
1Department of Cardiology, I.M. Sechenov University Hospital First Moscow State Medical University, Moscow, Russia
2Department of Cardiology, Yerevan State Medical University after Mkhitar Heratsi, Yerevan, Armenia
3Department of Cardiovascular Surgery, I.M. Sechenov University Hospital First Moscow State Medical University, Moscow, Russia
4Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, Pakistan
5Department of Food Science and Human Nutrition, University of Veterinary and Animal Sciences, Lahore, Pakistan

Background: Perfect heart valve prostheses have optimized hemodynamics, reduced surgical morbidity, long-lasting durability, and extended patient survival with greater quality of life. Mechanical valves are recommended; however, young children may need anticoagulant medication for life. In this study, we looked at the success rate and viability of aortic valve neocuspidization (AVNeo) surgery for a variety of aortic disorders.

Methods: A methodical search strategy was used to fully evaluate the AVNeo results. Boolean operators were used to combine important words like “Ozaki Procedure,” “Aortic Valve Neocuspidization,” “AVNeo,” and associated terms. Reputable databases such as PubMed, MEDLINE, Embase, Web of Science, and Scopus were the focus of our search. Study quality was assessed using a critical evaluation created with the Critical Appraisal Skills Programme tool.

Results: The findings are summarized in the ”Results” section that contains descriptive and critical analysis, ramifications, and explanations. According to research, AVNeo improved valve function and had few side effects. Aortic valve neocuspidization has a lower mean pressure gradient and a larger mean efficient orifice area than Trifecta. Aortic valve neocuspidization surgery reduces aortic valve regurgitation and pressure gradients. Postoperative echocardiograms indicated a decrease in peak and a rise in mean pressure gradient.

Conclusion: The Ozaki method restores a healthy laminar flow pattern while preventing bivalvular disease. Ozaki procedure should be explored for valve repair in infants with truncal valve and congenital aortic disease. Aortic valve tricuspidization with glutaraldehyde-treated autologous pericardium results in considerable effective orifice area, modest pressure gradients, and little regurgitation.

Keywords: Aortic valve, aortic valve tricuspidization, aortic valve diseases, aortic valve neocuspidization, AVNeo, Ozaki procedure, heart diseases

Samson S. Badalyan, Syune V. Markosyan, Alisher M. Ismailbaev, Andleeb Asghar, Aniq Ur Rehman. Outcomes of Ozaki Procedure/Aortic Valve Neocuspidization for Aortic Valve Diseases: A Systematic Review. Anatol J Cardiol. 2023; 27(11): 619-627

Corresponding Author: Samson S. Badalyan
Manuscript Language: English


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