ISSN 2149-2263 | E-ISSN 2149-2271
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Volume : 25 Issue : 12 Year : 2021
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Long-term results of long segment coronary artery lesions overlapped with novolimus-eluting DESolve scaffold: Disappointment or futuristic? [Anatol J Cardiol]
Anatol J Cardiol. 2021; 25(12): 912-919 | DOI: 10.5152/AnatolJCardiol.2021.25

Long-term results of long segment coronary artery lesions overlapped with novolimus-eluting DESolve scaffold: Disappointment or futuristic?

Ersin İbişoğlu1, Sinem Çakal2, Beytullah Çakal3, H. Murat Güneş3, Bedrettin Boyraz4, Bilal Boztosun3
1Department of Cardiology, Başakşehir Çam and Sakura City Hospital; İstanbul-Turkey
2Department of Cardiology, İstanbul Haseki Training and Research Hospital; İstanbul-Turkey
3Department of Cardiology, İstanbul Medipol University; İstanbul-Turkey
4Department of Cardiology, Tatvan State Hospital; Bitlis-Turkey

Objective: The data on using novolimus-eluting DESolve bioresorbable scaffolds (BVS) for long-segment coronary artery lesions remains insufficient. In this study, our main objective was to assess the long-term effects of the overlapping applications of both DESolve-DESolve and the drug-eluting stent (DES)-DESolve.
Methods: A single-centered study of 103 patients scheduled for DESolve placement for long-segment lesions (>28 mm) was conducted (October 2013 to November 2016). A DESolve-DESolve overlap was used on 43 patients and a DES-DESolve overlap on 60 patients. Acute procedural success and major adverse cardiac events (MACE) (stent thrombosis, targeted vessel revascularization, targeted lesion revascularization, and cardiac death) were evaluated. The patients were followed up for 48 months.
Results: Revascularization was performed on 4 (6.7%) patients in the DES-DESolve group and 5 (11.6%) patients in the DESolve–DESolve group for target lesion revascularization. Among the study population, 10 (9.7%) patients had MACE, including 5 (8.3%) patients in the DES–DESolve group and 5 (11.6%) patients in the DESolve–DESolve group.
Conclusion: The positive results of our study concerning the use of DESolve for the treatment of long coronary lesions demonstrate that BVS will emerge with new platforms and become non-inferior to the DES.

Keywords: bioresorbable vascular scaffold, DESolve, overlapping, hybrid strategy

Ersin İbişoğlu, Sinem Çakal, Beytullah Çakal, H. Murat Güneş, Bedrettin Boyraz, Bilal Boztosun. Long-term results of long segment coronary artery lesions overlapped with novolimus-eluting DESolve scaffold: Disappointment or futuristic?. Anatol J Cardiol. 2021; 25(12): 912-919

Corresponding Author: Ersin İbişoğlu, Türkiye
Manuscript Language: English