ISSN 2149-2263 | E-ISSN 2149-2271
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Integrating the Left Atrium Diameter to Improve the Predictive Ability of the Age, Creatinine, and Ejection Fraction Score for Atrial Fibrillation Recurrence After Cryoballoon Ablation [Anatol J Cardiol]
Anatol J Cardiol. 2023; 27(10): 567-572 | DOI: 10.14744/AnatolJCardiol.2023.2857

Integrating the Left Atrium Diameter to Improve the Predictive Ability of the Age, Creatinine, and Ejection Fraction Score for Atrial Fibrillation Recurrence After Cryoballoon Ablation

Gökay Taylan1, Murat Gök1, Alparslan Kurtul2, Abdulkadir Uslu2, Ayhan Küp3, Serdar Demir3, Kamil Gülşen3, Servet Altay1, Taylan Akgün3, Kenan Yalta1
1Department of Cardiology, Faculty of Medicine, Trakya University, Edirne, Türkiye
2Department of Cardiology, Faculty of Medicine, Hatay Mustafa Kemal University, Hatay, Türkiye
3Department of Cardiology, Kartal Koşuyolu High Specialization Training and Research Hospital, İstanbul, Türkiye

Background: Several clinical trials have assessed predictors for atrial fibrillation recurrence following cryoballoon catheter ablation. With these predictors, a practical and new scoring system can be developed to evaluate atrial fibrillation recurrence. The present study aimed to analyze the predictive value of the age, creatinine, and ejection fraction-left atrium score for potential recurrence of atrial fibrillation following cryoballoon catheter ablation in patients with symptomatic paroxysmal or persistent atrial fibrillation.

Methods: We retrospectively analyzed records of patients undergoing cryoballoon catheter ablation. atrial fibrillation recurrence was defined as an emerging atrial fibrillation episode around 12-month follow-up (with the exclusion of a 3-month blanking period). Univariate and multivariate analyses were performed to assess predictors of atrial fibrillation recurrence. In addition, receiver operating characteristic analysis was harnessed to evaluate the performance of the age, creatinine, and ejection fraction, left atrium score in determining the risk of atrial fibrillation recurrence.

Results: The study population comprised 106 subjects (age 52 ± 13 years, 63.2% women) with paroxysmal (84.9%, n = 90) or persistent (15.1%, n = 16) atrial fibrillation. age, creatinine, and ejection fraction, left atrium score was significantly higher in subjects with atrial fibrillation recurrence in comparison to those with the maintenance of sinus rhythm. However, on multivariate logistic regression analysis, only the age, creatinine, and ejection fraction, left atrium score (OR = 12.93, 95% CI: 2.22-75.21, P =.004) served as an independent predictor of atrial fibrillation recurrence following cryoballoon catheter ablation.

Conclusion: Age, creatinine, and ejection fraction, left atrium score had an independent association with the risk of atrial fibrillation recurrence in subjects with atrial fibrillation undergoing cryoballoon catheter ablation. Therefore, this score might potentially serve as a useful tool for risk stratification of patients with atrial fibrillation.

Keywords: Age, atrial fibrillation, creatinine, cryoballoon ablation, ejection fraction, left atrium, recurrence

Gökay Taylan, Murat Gök, Alparslan Kurtul, Abdulkadir Uslu, Ayhan Küp, Serdar Demir, Kamil Gülşen, Servet Altay, Taylan Akgün, Kenan Yalta. Integrating the Left Atrium Diameter to Improve the Predictive Ability of the Age, Creatinine, and Ejection Fraction Score for Atrial Fibrillation Recurrence After Cryoballoon Ablation. Anatol J Cardiol. 2023; 27(10): 567-572

Corresponding Author: Gökay Taylan
Manuscript Language: English


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