ISSN 2149-2263 | E-ISSN 2149-2271
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Early Systolic Lengthening Is Associated with SYNTAX Score in Patients with Non-ST-Elevation Acute Coronary Syndrome [Anatol J Cardiol]
Anatol J Cardiol. 2024; 28(2): 94-101 | DOI: 10.14744/AnatolJCardiol.2023.3064

Early Systolic Lengthening Is Associated with SYNTAX Score in Patients with Non-ST-Elevation Acute Coronary Syndrome

Tuba Unkun1, Çetin Geçmen1, Murat Çap2, Servet İzci1, Emrah Erdoğan3, Çağatay Önal4, Rezzan Deniz Acar1, Ruken Bengi Bakal1, Cihangir Kaymaz1, Nihal Özdemir1
1Department of Cardiology, Kartal Koşuyolu Heart Training and Research Hospital, İstanbul, Türkiye
2Department of Cardiology, Dr. Gazi Yaşargil Training and Research Hospital, Diyarbakır, Türkiye
3Department of Cardiology, Faculty of Medicine, Van Yüzüncü Yıl University, Van, Türkiye
4Department of Cardiology, İstanbul Training and Research Hospital, İstanbul, Türkiye

Background: Early systolic lengthening is a echocardiographic strain parameter previously used to determine the lesion severity in patients with stable coronary artery disease. In the present study, we aimed to evaluate the relationship between early systolic lengthening and anatomic SYNTAX score in troponin (−) and (+) groups among patients with non-ST-elevation acute coronary syndrome (ACS).

Methods: A total of 95 patients diagnosed with non-ST-elevation ACS were included in the prospective, non-randomized, single-center study. The patients were categorized into 2 groups as troponin (+) and troponin (−). The patients were evaluated in terms of echocardiographic, clinical, and angiographic parameters.

Results: The baseline characteristics, including age (58 ± 13 vs. 60 ± 10 respectively, P =.340), a history of hypertension (67.1% vs. 64%, respectively, P =.479), diabetes (28.6% vs. 32%, respectively, P =.467), global longitudinal strain (−14.37 ± 5.11 vs. −16.42 ± 3.93, respectively, P =.095), left ventricular ejection fraction (58.71 ± 8.73 vs. 57.20 ± 8.70, respectively, P =.263), and E/e’ (8.44 ± 2.13 vs. 8.33 ± 1.99, respectively, P =.785), were similar between troponin (+) and troponin (−) groups. Left ventricle end-systolic diameter (3.2 ± 0.78; 3.50 ± 0.74 vs. 3.2 ± 0.78, respectively, P =.031), left ventricle end-systolic volume (55.57 ± 32.17 vs. 38.28 ± 13.63, respectively, P =.013), left ventricle end-diastolic volume (115.31 ± 49.54 vs. 91.23 ± 20.57, respectively, P =.042), the rate of early systolic lengthening (65.7% vs. 28%, respectively, P =.001), the duration of early systolic lengthening (24.02 ± 31 ms vs. 15.56 ± 30.19 ms, respectively, P =.009), and the SYNTAX score (16 ± 11 vs. 10 ± 10, respectively, P =.023) were higher in the troponin (+) group. Furthermore, a significant correlation was found between early systolic lengthening and SYNTAX score (r = 0.43, P <.001).

Conclusion: The rate and duration of early systolic lengthening were higher in patients in the troponin (+) group. Early systolic lengthening is related to SYNTAX score in patients with non-ST-elevation ACS.

Keywords: Echocardiography, coronary artery disease, early systolic lengthening

Tuba Unkun, Çetin Geçmen, Murat Çap, Servet İzci, Emrah Erdoğan, Çağatay Önal, Rezzan Deniz Acar, Ruken Bengi Bakal, Cihangir Kaymaz, Nihal Özdemir. Early Systolic Lengthening Is Associated with SYNTAX Score in Patients with Non-ST-Elevation Acute Coronary Syndrome. Anatol J Cardiol. 2024; 28(2): 94-101

Corresponding Author: Tuba Unkun
Manuscript Language: English


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