The study aimed to compare major adverse cardiac and cerebrovascular events (MACCE), defined as a composite of death, stroke, myocardial infarction and symptom induced revascularization, and mortality within one year of randomization between two strategies: complete revascularization including non-culprit lesions percutaneous coronary intervention (PCI) during primary PCI(PPCI) versus complete revascularisation during the same hospital admission in multi-vascular coronary artery disease(MVD) patients presenting with ST-elevation myocardial infarction (STEMI) uncomplicated by cardiogenic shock.
We randomized in a 1: 1 manner 100 MVD patients with STEMI uncomplicated by cardiogenic shock who had undergone successful culprit-lesion PCI to either a strategy of complete revascularization with PCI of angiographically significant non-culprit lesions in the index PPCI procedure or to a strategy of complete revascularization during a second procedure that took place during the same hospital admission.
The first primary outcome was death within a timeframe of one year and the second a composite of MACCE within a year following complete revascularization.
Of the total number of patients monitored, 4% in each of the two groups was associated with the first primary outcome (P=0.9835) while the second primary outcome in 6% (P=0.9698). There was no statistical difference between outcomes in the two groups.
Among MVD patients with STEMI uncomplicated by cardiogenic shock, there was no difference regarding outcomes when using a strategy of complete revascularization of non-culprit lesions during PPCI or the same hospital admission.