ISSN 2149-2263 | E-ISSN 2149-2271
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Clinical Characteristics and Mid-term Follow-up in Children with Isolated Complete Atrioventricular Block [Anatol J Cardiol]
Anatol J Cardiol. 2023; 27(2): 106-112 | DOI: 10.14744/AnatolJCardiol.2022.2235

Clinical Characteristics and Mid-term Follow-up in Children with Isolated Complete Atrioventricular Block

Ayşe Sülü1, Hasan Candaş Kafalı1, Hacer Kamalı1, Serhat Bahadır Genç2, Ismihan Selen Onan2, Sertaç Haydin2, Alper Guzeltaş1, Yakup Ergul1
1Department of Pediatric Cardiology, University of Health Sciences İstanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Türkiye
2Department of Pediatric Cardiac Surgery, University of Health Sciences İstanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Education and Research Hospital, İstanbul, Türkiye

Background: Isolated complete atrioventricular block is a rare disease often associated with maternal autoantibodies. This study aimed to present the midterm data of patients at our clinic diagnosed with isolated complete atrioventricular block.

Methods: We evaluated 108 patients diagnosed with isolated complete atrioventricular block. Demographic data of the patients, electrocardiography, echocardiography, 24-hour Holter monitoring data, and follow-up and complications of the patients who underwent pacemaker implantation were evaluated retrospectively.

Results: The mean age of the patients at diagnosis was 5.51 ± 5.05 years. At the time of diagnosis, 74.8% of the patients had no symptoms associated with complete atrioventricular block. The most common symptom was fatigue. Pacemaker implantation was needed in 88 (81.4%) patients during follow-up. Significant bradycardia was the most
common pacemaker implantation indication. The mean battery life was 5.41 ± 2.65 years. The battery replacement-free period of 68 patients who underwent pacemaker implantation and continued their follow-up was 4.18 ± 2.89 (0.1-10) years. Pacemaker-related complications developed in 8 patients during follow-up. Left ventricular dysfunction developed (dyssynchrony induced) in 3 patients at follow-up, and all were paced from the right ventricular anterior wall. Those patients underwent cardiac resynchronization therapy and their left ventricular dysfunction improved.

Conclusion: Isolated complete atrioventricular block is a rare disease requiring careful clinical follow-up. Patients are often asymptomatic and significant bradycardia is the most common indication for pacemaker implantation. Left ventricular dysfunction is an important cause of morbidity, especially in patients with right ventricular anterior wall pacing. Physicians should be aware of left ventricular dysfunction during follow-up. Cardiac resynchronization therapy should be considered as a treatment option for left ventricular dysfunction.

Keywords: Isolated complete atrioventricular block, pacemaker, congenital complete atrioventricular block, cardiac resynchronization therapy

Ayşe Sülü, Hasan Candaş Kafalı, Hacer Kamalı, Serhat Bahadır Genç, Ismihan Selen Onan, Sertaç Haydin, Alper Guzeltaş, Yakup Ergul. Clinical Characteristics and Mid-term Follow-up in Children with Isolated Complete Atrioventricular Block. Anatol J Cardiol. 2023; 27(2): 106-112

Corresponding Author: Yakup Ergul
Manuscript Language: English


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Journal Citation Indicator: 0.18
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SCImago Journal Rank: 0.348

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