ISSN 2149-2263 | E-ISSN 2149-2271
Volume : 25 Issue : 12 Year : 2021
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The Anatolian Journal of Cardiology One-year outcomes of novel BioMime Morph tapered stent in long and multiple coronary artery lesions [Anatol J Cardiol]
Anatol J Cardiol. 2021; 25(12): 896-901 | DOI: 10.5152/AnatolJCardiol.2021.05763

One-year outcomes of novel BioMime Morph tapered stent in long and multiple coronary artery lesions

Yash Paul Sharma, Lipi Uppal, Prashant Panda, Soumitra Mohanty, Ganesh Kasinadhuni, Darshan Krishnappa, Saurabh Mehrotra, Ankur Gupta, Krishna Prasad, Krishna Santosh, Dinakar Bootla, Soumitra Ghosh
Department of Cardiology, Post Graduate Institution of Medical Education and Research (PGIMER); Chandigarh-India

Objective: Even with the immense progress achieved in the field of percutaneous coronary interventions (PCIs), treatment of diffuse long atherosclerotic coronary artery disease continues to remain a challenge for durable outcomes. The downstream reduction in diameter along the lesion length of a coronary artery may compel the cardiologist to use either 2 overlapping stents of different diameters or a single long stent leading to stent-vessel mismatch at the edges. Recently, Meril Life Sciences Pvt. Ltd., India, has introduced a long-tapered sirolimus-eluting stent (SES) system, BioMime Morph, which conforms to the normal tapered geometry of coronary arteries along with adequate lesion coverage. In this study, we aimed to provide real world experience regarding the safety and efficacy of the BioMime Morph SES over a follow-up of one year.
Methods: This was a single center, retrospective study involving 172 participants who underwent PCI with the BioMime Morph SES. Mean length of the target lesion was 34.4±10.4 mm, and mean stent length was 53.2±8.7 mm. The most frequent revascularized vessel was the left anterior descending artery (LAD) in 97 lesions (54.4%).
Results: Major adverse cardiac events (MACE) (defined as a composite of target vessel myocardial infarction, target lesion revascularization, and death due to a cardiac cause) at 1, 6, and 12 months were seen in 4 (2.3%), 7 (4.0%), and 8 (4.7%) patients, respectively. Overall, 5 cardiac deaths and 2 definite stent thrombosis were observed in the study.
Conclusion: The study suggests that the novel BioMime Morph SES is an effective and a safe option for PCI in the treatment of long diffuse atherosclerotic lesions.

Keywords: diffuse disease, long lesions, multiple lesions, BioMime Morph, tapered stent, percutaneous coronary revascularization

Yash Paul Sharma, Lipi Uppal, Prashant Panda, Soumitra Mohanty, Ganesh Kasinadhuni, Darshan Krishnappa, Saurabh Mehrotra, Ankur Gupta, Krishna Prasad, Krishna Santosh, Dinakar Bootla, Soumitra Ghosh. One-year outcomes of novel BioMime Morph tapered stent in long and multiple coronary artery lesions. Anatol J Cardiol. 2021; 25(12): 896-901

Corresponding Author: Prashant Panda, India
Manuscript Language: English