ISSN 2149-2263 | E-ISSN 2149-2271
Volume : 25 Issue : 11 Year : 2021
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The Anatolian Journal of Cardiology Echocardiographic findings in patent ductus arteriosus-associated infective endarteritis [Anatol J Cardiol]
Anatol J Cardiol. 2021; 25(11): 774-780 | DOI: 10.5152/AnatolJCardiol.2021.36156

Echocardiographic findings in patent ductus arteriosus-associated infective endarteritis

Huitzilihuitl Saucedo-Orozco1, Jesús Vargas- Barrón2, Clara A. Vázquez- Antona3, Francisco Castillo- Castellón4
1Department of Cardioneumology, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social; Mexico City-México
2Department of Pharmacology, Instituto Nacional de Cardiología Ignacio Chávez; Mexico City-México
3Department of Pediatric Echocardiography, Instituto Nacional de Cardiología Ignacio Chávez; Mexico City-México
4Department of Tomography, Instituto Nacional de Cardiología Ignacio Chávez; Mexico City-México

Background. Infectious endarteritis associated with patent ductus arteriosus (PDA-IE) is an uncommon complication in the era of antibiotics. However, it implies a clinical challenge in patients with a fever of undetermined origin; Two-dimensional transthoracic echocardiography (TTE) performs a fundamental role in diagnosis and follow-up.
Methods. A retrospective analysis was then made of the data of all patients admitted at our center with PDA-IE within 15 years, and a review of the literature regarding diagnosis, TTE findings, and treatment was performed.
Results. A total of 17 patients were identified. The mean age was 17.8 years. The TTE done in all patients confirmed the PDA and PA vegetations diagnosis; in five cases, one vegetation was present; in three cases, two vegetations were found, and in the nine remaining cases, three or more vegetations were observed. In two-thirds of the cases, the vegetations' size was 3 to 28 mm, and the principal morphology was filiform. In all cases, at least one of the vegetations was developed in the DA's lateral wall. Pulmonary valve (PV) was affected in 41% of the patients and caused low to moderate valvular regurgitation. Pulmonary embolism was present in 7 cases and pulmonary aneurism in one case.
Conclusions. Decreased incidence of PDA-IE has been currently achieved with early antibiotic therapy. However, today, this complication carries a significant risk of valve damage and other cardiac structures' involvement.

Keywords: Patent ductus arteriosus, Infectious endarteritis, Echocardiography, Congenital heart disease.











Huitzilihuitl Saucedo-Orozco, Jesús Vargas- Barrón, Clara A. Vázquez- Antona, Francisco Castillo- Castellón. Echocardiographic findings in patent ductus arteriosus-associated infective endarteritis. Anatol J Cardiol. 2021; 25(11): 774-780

Corresponding Author: Huitzilihuitl Saucedo-Orozco, Mexico
Manuscript Language: English