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Volume : 16 Issue : 3 Year : 2021
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The Anatolian Journal of Cardiology Renal artery stenosis and mean platelet volume [Anatol J Cardiol]
Anatol J Cardiol. 2016; 16(3): 197-201 | DOI: 10.5152/AnatolJCardiol.2015.6102

Renal artery stenosis and mean platelet volume

Muhammet Raşit Sayın1, Nesimi Yavuz1, Turgut Karabağ1, Mehmet Ali Çetiner3, İbrahim İlker Öz2, Orhan Alper Güngördük4, Mustafa Aydın1
1Departments of Cardiology, Faculty of Medicine, Bülent Ecevit University; Zonguldak- Turkey
2Radiology, Faculty of Medicine, Bülent Ecevit University; Zonguldak- Turkey
3Department of Cardiology, Karadeniz Ereğli State Hospital; Zonguldak- Turkey
4Department of Cardiology, Çaka Vatan Hospital; Kahramanmaraş- Turkey

Objective: Increased mean platelet volume (MPV) has been reported in various atherosclerotic diseases. The aim of our study was to investigate the relationship between the atherosclerotic renal artery stenosis (ARAS) and various hematological parameters including MPV.
Methods: This study was performed with a retrospective review of the angiographic images of patients who underwent renal angiography at Bülent Ecevit University catheter laboratory between January 2004 and December 2009. The patients were trichotomized into three groups based on the presence and severity of renal artery stenosis (RAS). Group 1 included patients with a critical RAS (33 patients; 18 female (F), 15 male (M); mean age 61.6±11.5 years), group 2 consisted of patients with non-critical RAS (26 patients; 15 F, 11 M; mean age 58.1±11.3 years), and group 3 was composed of patients without RAS (69 patients; 38 F, 31 M; mean age 53.5±11.9 years). Demographic data, complete blood count, and biochemical parameters were compared between the groups.
Results: Comparison of the hematological parameters revealed that MPV and platelet distribution width were significantly higher in group 1 than in group 2 and 3 (8.96±0.99 fL versus 8.35±0.76 fL, 8.31±0.79 fL, respectively; p=0.001; 16.53±0.58% versus 16.19±0.56%, 16.29±0.53%, respectively; p=0.04).
Conclusion: MPV levels are higher in patients with ARAS. Considering both the effect of platelets on atherosclerosis and their close association with other risk factors, MPV level may be an important factor in pathogenesis of ARAS. (Anatol J Cardiol 2016; 16: 197-201)

Keywords: mean platelet volume, platelet, renal artery stenosis, atherosclerosis, complete blood count

Muhammet Raşit Sayın, Nesimi Yavuz, Turgut Karabağ, Mehmet Ali Çetiner, İbrahim İlker Öz, Orhan Alper Güngördük, Mustafa Aydın. Renal artery stenosis and mean platelet volume. Anatol J Cardiol. 2016; 16(3): 197-201

Corresponding Author: Muhammet Raşit Sayın, Türkiye