ISSN 2149-2263 | E-ISSN 2149-2271
The Anatolian Journal of Cardiology
Evaluation of Myocardial Strain by 2-Dimensional Speckle Tracking Echocardiography in Patients with Facioscapulohumeral Muscular Dystrophy [Anatol J Cardiol]
Anatol J Cardiol. 2022; 26(7): 525-531 | DOI: 10.5152/AnatolJCardiol.2022.907

Evaluation of Myocardial Strain by 2-Dimensional Speckle Tracking Echocardiography in Patients with Facioscapulohumeral Muscular Dystrophy

Ferhat Işık1, Abdurrahman Akyüz1, Murat Çap1, Askeri Türken2, Süleyman Varsak3, Erkan Baysal1
1Department of Cardiology, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey
2Department of Physical Therapy and Rehabilitation, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey
3Bingöl University Health Services Vocational School, Bingöl, Turkey

Background: Facioscapulohumeral muscular dystrophy is one of the most common congenital muscle disorders. Whether facioscapulohumeral muscular dystrophy causes cardiac involvement is still controversial. Although electrocardiography and conventional echocardiography studies have been performed, there is no data on strain echocardiography in facioscapulohumeral muscular dystrophy. Our study aims to compare the myocardial strain parameters by 2-dimensional speckle tracking echocardiography in patients with facioscapulohumeral muscular dystrophy and the normal group.

Methods: This prospective single-center study included 35 patients with facioscapulohumeral muscular dystrophy and 54 control patients. Demographic, clinical, and laboratory parameters of both groups were compared. In addition to conventional echocardiography images, myocardial strain parameters were performed using 2-dimensional speckle tracking echocardiography.

Results: The median age of the study population was 25 (19-35 IQR) and 51 (57.3%) of them were male. Left ventricle-global circumferential strain was significantly lower in the facioscapulohumeral muscular dystrophy group than in the normal group [−20.3 (−22.0; −19.0) vs. −21.6 (−22.5; −20.0), P =.020]. Two-dimensional speckle tracking echocardiography findings except left ventricle-global circumferential strain [for left ventricle-global longitudinal strain P =.259, for left ventricle-global radial strain P =.338, for right ventricle-global circumferential strain P=.250, and for right ventricle-free wall longitudinal strain P =.288] were similar in both groups.

Conclusions: As a result of our study, there was no significant difference between 2-dimensional speckle tracking echocardiography parameters other than the left ventricle-global circumferential strain between facioscapulohumeral muscular dystrophy and normal groups.

Keywords: Cardiac involvement, echocardiography, imaging, FSHD, strain

Ferhat Işık, Abdurrahman Akyüz, Murat Çap, Askeri Türken, Süleyman Varsak, Erkan Baysal. Evaluation of Myocardial Strain by 2-Dimensional Speckle Tracking Echocardiography in Patients with Facioscapulohumeral Muscular Dystrophy. Anatol J Cardiol. 2022; 26(7): 525-531

Corresponding Author: Ferhat Işık
Manuscript Language: English


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