ISSN 2149-2263 | E-ISSN 2149-2271
The Anatolian Journal of Cardiology
Global confusion on the diagnostic criteria for metabolic syndrome: What is the point that guidelines can not agree? [Anatol J Cardiol]
Anatol J Cardiol. 2008; 8(2): 149-153

Global confusion on the diagnostic criteria for metabolic syndrome: What is the point that guidelines can not agree?

Selçuk Dağdelen1, Tolga Yıldırım2, Tomris Erbaş1
1Hacettepe Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı Ankara, Türkiye
2Hacettepe Üniversitesi Tıp Fakültesi, Endokrinoloji ve Metabolizma Ünitesi Anabilim Dalı Ankara, Türkiye

Several international and national associations have proposed their own diagnostic criteria for metabolic syndrome. Regarding the heterogeneity of these guidelines, some authors refused the usage of metabolic syndrome definition. Here we aimed to analyze the differences between the diagnostic criteria proposed for metabolic syndrome. We reviewed and compared these different guidelines’ criteria. We conclude that, despite the heterogeneity, there is a conceptual agreement on the definition of metabolic syndrome. But cut-off values and selection of diagnostic parameters are still conflicting. Diagnostic or definitive components of the syndrome (i.e., obesity, insulin resistance) should be considered separately from the associated-conditions (i.e., polycystic ovary, obstructive sleep apnea, microalbuminuria, non-alcoholic steatohepatitis etc.) of metabolic syndrome, during the course of diagnosis. Maintenance of the metabolic syndrome as a diagnostic category would still seem to be useful for an effective multiple cardiovascular risk prediction.

Keywords: Metabolic syndrome, diagnostic criteria, guidelines, obesity, insulin resistance

Selçuk Dağdelen, Tolga Yıldırım, Tomris Erbaş. Global confusion on the diagnostic criteria for metabolic syndrome: What is the point that guidelines can not agree?. Anatol J Cardiol. 2008; 8(2): 149-153
Manuscript Language: English


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