ISSN 2149-2263 | E-ISSN 2149-2271
Volume : 16 Issue : 9 Year : 2021
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The Anatolian Journal of Cardiology High blood pressure: An obscuring misnomer? [Anatol J Cardiol]
Anatol J Cardiol. 2016; 16(9): 713-719 | DOI: 10.14744/AnatolJCardiol.2016.7054

High blood pressure: An obscuring misnomer?

Emre Aslanger1, Murat Sezer2, Sabahattin Umman2
1Department of Cardiology, Yeditepe University Hospital; İstanbul-Turkey
2Department of Cardiology, İstanbul Faculty of Medicine, İstanbul University; İstanbul-Turkey

High blood pressure (BP) has been identified as a major risk factor for cardiovascular complications. Although two-way association between BP and hypertensive complications makes hypertension a near-ideal biomarker, BP as “the cause” for the complications of HT per se still needs more evidence. Another entirely possible hemodynamic candidate for causing hypertensive cardiovascular adverse events can be flow or its iterations, which might have escaped the attention because of its perfect correlation with pressure and harder technical measurement. In this article, we analyze the evidence in hand to compare flow- and pressure-related phenomena to delineate which of the two is the dominant mediator of complications related to hypertension and should be the target for therapy. A “flow-” rather than a “pressure-” based factor, as the causative or major driving mediator of common hypertensive complications, may change our understanding of hypertension pathophysiology. (Anatol J Cardiol 2016; 16: 713-9)

Keywords: Atherosclerosis, cardiovascular outcomes, coronary heart disease, hypertension, stroke

Emre Aslanger, Murat Sezer, Sabahattin Umman. High blood pressure: An obscuring misnomer?. Anatol J Cardiol. 2016; 16(9): 713-719

Corresponding Author: Emre Aslanger, Türkiye