Prevalence of Coronary Artery Disease in Patients Undergoing Valvular Operation Due to Rheumatic Involvement

Bozbaş, Hüseyin; Yıldırır, Aylin; Alparslan  Küçük, Mehmet; Özgül, Aliseydi; Atar, İlyas; Sezgin, Atilla; Aşlamacı, Sait; Emin  Korkmaz, Mehmet; Özin, Bülent

Original Investigation

Hüseyin Bozbaş ¹ , Aylin Yıldırır ² , Mehmet Alparslan Küçük ³ , Aliseydi Özgül ³ , İlyas Atar ¹ , Atilla Sezgin ⁴ , Sait Aşlamacı ⁵ , Mehmet Emin Korkmaz ⁶ , Bülent Özin ⁷

¹Department of Cardiology, Faculty of Medicine, Başkent University, Ankara, Turkey
²Department of Cardiology Surgery School of Medicine, Başkent University, Ankara, Turkey
³Department of Cardiology Surgery, School of Medicine, Baflkent University, Ankara, Turkey
⁴Department of Cardiovascular Surgery, School of Medicine, Başkent University, Ankara, Turkey
⁵Başkent Universitesi Hastanesi, Kalp Damar Cerrahi Kliniği, Ankara, Türkiye
⁶Department of Cardiology, Medical Faculty, Başkent University, Ankara, Turkey
⁷Başkent Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Ankara

Anatol J Cardiol 2004; 3(4): 223-226 PubMed ID: 15355824

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Abstract

Objective: Rheumatic heart disease is still a major health problem in developing countries. The impact of coronary artery disease (CAD) on or its relation to rheumatic fever is not well established. We aimed to evaluate the prevalence of CAD and atherosclerotic risk factors in patients who underwent valvular surgery due to rheumatic heart disease. Materials and Methods: The records of 346 patients who had undergone rheumatic valvular surgery in a university hospital between 1996 and 2002 were evaluated. Results: Coronary angiography was performed in 218 (63%) patients, of whom 41 (18.8%) had CAD. The mean age of the patients having CAD and normal coronary arteries were 57.3 and 50.5 years respectively (p<0.001). In the study population patients with CAD had significantly increased prevalence of diabetes mellitus (14.6% vs. 4.5%; p=0.02), hypertension (36.6% vs. 16.4%; p=0.003), smoking (51.2% vs. 23.2%; p=0.001) and family history of CAD (39.5% vs. 20.0%; p=0.01) compared to patients with normal coronary arteries. However, the prevalence of dyslipidemia was similar in both groups (45.9% vs. 36.4%; p=0.1). Conclusion: These findings suggest that coronary artery disease prevalence in rheumatic valvular disease patients is similar to the normal population of same age. In cases where invasive assessment of valvular lesions is not indicated we suggest coronary angiography to be performed only in patients having clinical suspicion of CAD or multiple risk factors.

Keywords: Rheumatic valvular heart disease, coronary artery disease, coronary risk factors.

Romatizmal Kapak Hastalığı Nedeniyle Kapak Ameliyatı Yapılan Hastalarda Koroner Arter Hastalığı Prevalansı

Hüseyin Bozbaş¹ , Aylin Yıldırır² , Mehmet Alparslan Küçük³ , Aliseydi Özgül³ , İlyas Atar¹ , Atilla Sezgin⁴ , Sait Aşlamacı⁵ , Mehmet Emin Korkmaz⁶ , Bülent Özin⁷

¹Department of Cardiology, Faculty of Medicine, Başkent University, Ankara, Turkey
²Department of Cardiology Surgery School of Medicine, Başkent University, Ankara, Turkey
³Department of Cardiology Surgery, School of Medicine, Baflkent University, Ankara, Turkey
⁴Department of Cardiovascular Surgery, School of Medicine, Başkent University, Ankara, Turkey
⁵Başkent Universitesi Hastanesi, Kalp Damar Cerrahi Kliniği, Ankara, Türkiye
⁶Department of Cardiology, Medical Faculty, Başkent University, Ankara, Turkey
⁷Başkent Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Ankara

The Anatolian Journal of Cardiology 2004; 3(4): 223-226 PMID: 15355824

Anahtar Kelimeler: Romatizmal kapak hastalığı, koroner arter hastalığı, koroner risk faktörleri