ISSN 2149-2263 | E-ISSN 2149-2271
Volume : 25 Issue : 12 Year : 2021
Quick Search



The Anatolian Journal of Cardiology Tp-e/QTc ratio, SYNTAX, and GRACE score in patients who underwent coronary angiography owing to acute coronary syndrome [Anatol J Cardiol]
Anatol J Cardiol. 2021; 25(12): 887-895 | DOI: 10.5152/AnatolJCardiol.2021.31

Tp-e/QTc ratio, SYNTAX, and GRACE score in patients who underwent coronary angiography owing to acute coronary syndrome

Kadriye Gayretli Yayla1, Çağrı Yayla3, Mehmet Akif Erdöl3, Mustafa Karanfil3, Hamza Sunman2, Faruk Aydın Yılmaz2, Nail Burak Özbeyaz2, Ayşe Nur Özkaya İbiş2, Murat Tulmaç2
1Department of Cardiology, Health Sciences University, Dışkapı Yıldırım Beyazıt Training and Research Hospital; Ankara-Turkey; Department of Cardiology, Health Sciences University, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital; Ankara-Turkey
2Department of Cardiology, Health Sciences University, Dışkapı Yıldırım Beyazıt Training and Research Hospital; Ankara-Turkey
3Department of Cardiology, Health Sciences University, Ankara City Hospital; Ankara-Turkey

Objective: Ventricular arrhythmias following acute coronary syndrome (ACS) range from benign to life-threatening fatal arrhythmias. Tpeak-end (Tp-e) interval has been shown to be an important parameter in the assessment of repolarization dispersion. We aimed to evaluate the relationship between SYNTAX and Global Registry of Acute Coronary Events (GRACE) risk score calculated on admission and Tp-e interval and Tp-e/QTc ratio.
Methods: A total of 421 patients were included in the study. The patients were divided into 2 groups as low SYNTAX score (≤22) and moderate and high risk SYNTAX score (>22). According to the GRACE risk score, the patients were divided into 2 groups; high-risk patients ≥140 and <140 low-risk patients.
Results: In the group with SYNTAX score >22, the Tp-e interval (p<0.001) and Tp-e/QTc ratio (p<0.001) was found to be significantly higher than in the group with a SYNTAX score ≤22. Tp-e interval (p<0.001) and Tp-e/QTc ratio (p=0.002) was higher in patients with GRACE risk score ≥140 compared with patients with a GRACE risk score <140. The correlation between Tp-e interval and Tp-e/QTc ratio and SYNTAX score (r=0.489; p<0.001) and GRACE risk score (r=0.274; p<0.001) were found to be significant. A significant and independent correlation was found between the SYNTAX score and Tp-e/QTc ratio (β=0.385; p<0.001).
Conclusion: Tp-e interval and Tp-e/QT ratio increased in patients with severe coronary artery disease assessed with SYNTAX score. Tp-e interval and Tp-e/QT ratio increased in patients with a high GRACE risk score.

Keywords: acute coronary syndrome, GRACE risk score, SYNTAX score, Tp-e/QTc

Kadriye Gayretli Yayla, Çağrı Yayla, Mehmet Akif Erdöl, Mustafa Karanfil, Hamza Sunman, Faruk Aydın Yılmaz, Nail Burak Özbeyaz, Ayşe Nur Özkaya İbiş, Murat Tulmaç. Tp-e/QTc ratio, SYNTAX, and GRACE score in patients who underwent coronary angiography owing to acute coronary syndrome. Anatol J Cardiol. 2021; 25(12): 887-895

Corresponding Author: Kadriye Gayretli Yayla, Türkiye
Manuscript Language: English